伴有紧张性症状的女性双相情感障碍的临床研究

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1、伴有紧张性症状的女性双相情感障碍的临床研究【摘要】目的：探讨伴紧张症状女性双相情感障碍的临床特点。方法：回顾性分析入院时伴紧张症状、出院时符合TCD-10的紧张型精神分裂症（A组）与双相情感障碍症（B组）各30例患者的临床资料。结果：A、B两组患者病期分别为（37.9±17.7）d、（18.0±13.4）d；入院诊断符合率分别为93.3%、60.0%,差异均有统计学意义（P〈0.05）。临床现象的比较：B组起病急，病前受应激因素影响易轻躁狂，伴紧张症状时多呈“作态”、“装相”戏剧化行为，治疗1周内可

2、缓解且反应敏感于A组。A组患者症状缓解后的BPRS评定显示“激活性”因子、“焦虑忧郁”因子分值均明显高于B组（P〈0.05）,B组患者症状缓解后的BPRS评定显示“缺乏活力”因子，“敌对猜疑”因子，“思维障碍”因子分值均明显高于A组（P<0.05）o结论：紧张性症状与精神分裂症、双相情感障碍冇关，但两者的起病形式、应激影响、性格特点以及治疗反应性差异显著，且症状缓解后A组的“缺乏活力”、“敌对猜疑”、“思维障碍”明显区别于B组的兴奋、焦虑等情绪化特点。【关键词】紧张；女性；双相情感障碍；精神分裂症【

3、Abstract】Objective:Toinvestigatetheclinicalcharacteristicsofbipolardisorderinwomenwithnervoussymptoms.Method:Theclinicaldataof30patientswithnervoussymptomsatthetimeofadmission,atdischargeinaccordancewiththeICD-10nervoustypeschizophrenia(thegroupA)and30

4、patientswithbipolardisorder(thegroupB)wereretrospectivelyanalyzed・Result：ThediseasestageofgroupAandgroupBwere(37.9±17.7)d,(18.0±13.4)d；admissiondiagnosiscoincidenceratewere93.3%,60.0%respectively,thedifferenceswerestatisticallysignificant(P<0.05)•Thecl

5、inicalphenomenonofcomparison：thegroupBacuteonset,beforethediseaseaffectedbystressfactorseasyhypomania，mostlywhenaccompaniedbynervoussymptoms"asastate〃，/zmannerisms^dramaticbehavior,within1weekoftreatmentcouldrelieveandthereactionwassensitivetothegroupA

6、.BPRSassessmentaftersymptomremissionshowedthatthescoresofz，activatedz，,"anxietydepression'7factorsingroupAwerehigherthanthoseingroupB(P<0.05)•〃thelackofvitality"，"hostilesuspicion'7factorand"thoughtobstacle”factorscoreingroupAweresignificantlyhighertha

7、nthoseingroupA(P<0.05).Conclusion:Nervoussymptomsassociatedwithschizophreniaandbipolardisorders,butthedifferencesarestatisticallysignificantintheonsetofbothforms,theimpactofstress,personalitycharacteristicsandtreatmentresponseofthetwogroups.Andaftersym

8、ptomremission,the"lackofvitality","hostilesuspicionthoughtdisorder"ofgroupAaresignificantlydifferentfromtheexcitement,anxietyandotheremotionalcharacteristicsofgroupB.[Keywords]Nervous；Women；Bipolardisorder；SchizophreniaFirst-author9sadd