资源描述：
《胸主动脉超声探查粥样硬化斑块诊断及预测冠心病的临床意义》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、胸主动脉超声探杏粥样硬化斑块诊断及预测冠心病的临床意义【关键词】胸主【摘要】目的病理和X线研究C证实主动脉粥样硬化斑块和冠心病相关，但一直未应用于临床。通过胸主动脉超声探查粥样硬化斑块验证其是否为诊断冠状动脉粥样硬化性心脏病(冠心病)的标志。方法对65例患者行主动脉超声探查粥样硕化斑块。经胸主动脉超声诊断粥样硕化斑块的标准为胸主动脉管腔线样或局部增厚，不规则冋声增强和内膜增厚或钙化。结果65例患者中44例冠脉造彩证实至少1支冠状动脉粥样硬化，冠状动脉左主干狭窄>50%,左前降支、左回旋支、右冠脉狭窄>70%o44例患者中39例胸主动脉超芦证实存在粥样硬化斑块。65例患者中21例冠脉造影止
2、常或非粥样硬化性管腔狭窄，2例胸主动脉超声探查存在粥样换化斑块。胸主动脉超声诊断上动脉粥样硬化斑块的敏感性为89%,诊断冠心病的特异性为89%o主动脉粥样硬化斑块对冠心病的肯定预测价值是95%,否定预测价值是79%o结论胸主动脉超声探查粥样破化斑块是预测冠心病的标志，临床应进一步研究。aorticplaque:AmarkerforcoronaiyatheroscleroticheartdiseasesHuoMeng,GaoYajun,ZhangGang,etal.AffiliatedHospitahAcademyofMedicalScienceofHebei,Shijiazhuang05
3、0011.[Abstract】ObjectiveTotestthehypothesisthatatheroscleroticplaqueinthethoracicaortadetectedbytho~racicaorticechocardiographicallyisamarkerforcornaryatheroscleroticheartdisease.Previouspathologicandroentgenographicstudiessuggestedarelationbetweenaorticplaqueandcoronaryatheroscleroticheartdiseas
4、ebutlackedclinicalutility.MethodsWeperformedthoracicaorticechocardiographical1yon65patients(32womenand33men,aged24to80years[mean60±12years]whohadpreviouslyundergonecardiaccatheterizationwithcoronaryangiography.Theclinicalindicationsforangiographywereangina(n=27),valvularheartdisease(n=16),positiv
5、enoninvasiveevaluationforischemiawithoutangina(n=7),postmyocardialinfraction(n=6),familialhypercholes~terolemia(n=5),coronarycameralfistula(n=l),atrialmyxoma(n=2),andsuspectedaorticdissection(n=l).Allpatientsunderwentchoracicaorticechocardiographywithimagingofthethoracicaorta.Thecriteriausedtodia
6、gnoseatheroscleroticplaqueonthoracicaorticechocardiographywerethepresenceorlinearandfocalincreasedechodensitywithlumenirregularityandthickeningofcalcificationoftheaorticintima.ResultsIn44ofthe65patients,obstruc~tivecoronaryarterydiseasewasdetectedbyangiographyinatleastonevessel,leftmaincoronaryat
7、erystenosis>50%or>70%stenosisintheleftanteriordescending,rightcoronaryorleftcircumflexarterydistribution.In39ofthe44,atheroscleroticplaquewasdetectedinthethoracicaortabythoracicaorticechocardiography.2lofthe65patientsh
