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1、腹腔镜手术中意外胆囊癌临床处理分析作者:牛伟亚,克力木,张成,阿扎提,艾克拜尔,王自立【摘要】目的:探讨在腹腔镜胆囊切除术(LC)中意外发现胆囊癌的治疗方法。方法:对14例LC时意外发现的胆囊癌患者的临床资料进行回顾性分析。结果:4例NevinI、II期患者行单纯LC,2例III期和3例IV期患者行LC中转开腹+局部淋巴结清扫术+肝脏楔形切除术,5例V期患者行胆囊姑息性切除术。全组意外胆囊癌的发生率为0.06%o结论:I期的意外胆囊癌行LC可达到根治目的,II期行胆囊切除+肝脏部分切除+术后化疗,III、IV期需行胆囊癌根治术,V期根据情况行胆囊切除或姑息手
2、术。【关键词】腹腔镜;胆囊癌AnalysisofclinicalmanagementforunsuspectedgallbladdercarcinomasdiscoveredduringlaparoscopyNIUWeiya,KELimu,ZHANGCheng,etal.Dept,ofLaparoscopicSurgery,People7sHospitalofXinjiangUygurAutonomousRegion,Urumqi830001,China[Abstract】0bjective:Toassessthesurgicalapproachesforu
3、nsuspectedgallbladdercarcinomas(UGC)discoveredduringlaparoscopiccholecystectomy(LC).Methods:Basedonclinicaldata,retrospectiveanalysiswerecarriedoutfor14patientswithUGCdiscoveredduringLC.Results:4patientswithtumorsofNevin'sstageIorstageIIunderwentsimpleLCalone;2patientswithtumorsofs
4、tageIIIand3patienrswithtumorsofstageIVwereconvertedtolaparotomy,andperformedwedgeexcisionofgallbladderbedandregionallymphadenectomy;5patientswithtumorsofstageVwereemployedforpalliativecholecystectomy.Inthisseries,theincidenceofUGCwas0.06%.Conclusions:UGCofStage1maybecuredaftersimpl
5、eLC,whiletheseofstageIIshouldreceivecholecystectomyandpartialliverresectionwithpostoperativechemitherapy.UGCofstagelllandIVshouldbereferredforradicaloperation,andthoseofstageVcanbetreatedwithcholecystectomyorotherpalliativesurgicalprocedures.[Keywords】Laparoscopy;Gallbladdercarcino
6、ma腹腔镜胆囊切除术(LC)目前已成为治疗胆囊良性疾病的标准术式,在术中或术后病理检查发现的胆囊癌被称为意外胆囊癌(UGC)o我院自1992〜2005年行LC24000余例,发现UGC14例,现就其诊断与处理方法进行分析。1资料与方法11临床资料本组男3例,女11例,33〜79岁,平均66岁。7例以反复右上腹疼痛或不适为主要症状,最长病史达35年,3例有发热、恶心、呕吐,3例体检发现胆囊隆起性病变,1例既往有胃癌手术史,全组病例均无黄疸症状,B超检查均为急、慢性胆囊炎并胆囊结石或胆囊息肉,术前均未行CT检查,9例见胆囊壁增厚〉05cm,术前诊断胆囊炎胆结石1
7、1例,胆囊隆起性病变3例。12Nevin分期与手术方式14例均先行LC术,全组病例术后病理诊断为胆囊癌,4例Nevin分期为I、II期的患者行LC后均未再行手术,5例III、IV期因胆囊实变或与周围组织粘连明显行中转开腹手术胆囊切除术+局部淋巴结清扫,2例V期行局部淋巴结清扫+肝脏楔行切除术,其余3例V期均行胆囊姑息性切除术,其中1例术后行介入化疗,1例剑突下Trocar穿刺孔种植转移,1例术后证实为转移性癌。2结果14例中有3例为低分化腺癌,其余为腺癌。4例患者失访,10例随访中4例死亡,其中Nevin分期I、II期的4例患者均生存未复发,1例包块切口种植
8、(II),4例IV〜V期半年至1年内死亡。3讨论LC