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时间:2019-10-08
《症状性大脑中动脉M1段闭塞后存活患者的预后及其危险因素》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据·570-中华老年心嘧血管病杂志2012年6月第14差第6期c梳j(;c由tr}kart既缸nvcsscl巧s,J恤20l2。v0114.Nq6.缺血性脑血管病研究.症状性大脑中动脉M1段闭塞后存活患者的预后及其危险因素田利丽,岳炫烨,张海峰,孙文珊,郭芮兵,徐格林,刘新峰摘要:日的探讨症状性大脑中动脉M1段闭塞后存活患者的预后及其危险因素。方法选取大脑中动脉M1段闭塞导致首次脑梗死且1个月时仍存活的患者126倒.夫脑中动脉Ml段闭塞经脑血管造影证实,对患者进行随访研究,以脑卒中再发或死亡为终点事件。牧集驻血管病的危险因素和血管病变特点,用
2、单因素和多圆素co】‘回归模型进行危险因素分析。结幂126例大脑中动脉闭塞后存活患者中.平均随访35.7个月(3~66个月)。终点事件发生率为14.3%.其中脑梗死再发13例。死亡5例,脑出血2倒。单因素和多因素分析显示,冠心病和伴其他血管狭窄数与患者预后明显相关(()R一8.893,95%CJ:2.885~27.418.P=0.000)。结论症状性大脑中动脉M1段闭塞存活患者长期预后良好,影响患者预后的因素是冠心病和伴有其他脑血管病变。关键词:颅内动脉硬化;脑缺血;冠心痛;脑血管造影术;预后l危险因素PrognosisofsurViVedpati
3、entswithsymptomaticocclusionin】Ⅵ1segmentofmiddlecerebralarteryTIANI.i—h,YUEXuan—ye,ZHANGHai—feng,etal(DPp口坩研君小o,N£Mr0Zogy,_,in“"gH椰户i幻z,N日可f行g210002,J抽”gs“P阳t『£n卵,(洗ina)Abst憎ct:objectiveTostudytheprognosisofsurvivedpatientswithsymptomaticocclusionin^压1segmentofmiddlecerebralar
4、teryandhsriskfactors.Methodsonehundredandtwenty-s主xsurvivedpatientswithcerebralinfarctionduetolmonthmiddlecerebralarteryocclusioncon—firmedbydigitalsubtractangiographyweref01lowedup.Relapseofcerebralstrokeanddeathwereconsideredastheendevents.1之iskfactorsfortheircerebrovascular
5、diseasewereanalyzedwithunivariateandmultivariateCoxregressionmodel.ResuItsThepatientswerefoIlowedupfor35.7months(3—66months).Theincidenceofendeventswas14.3%.Cerebralinfarctionre—curredin13patients,5patientsdied,andcerebraIhemorrhagewasfoundin2patients(1diedofcerebralhemorrhage
6、,and1diedofcerebralinfarction).UnivariateandmultivariateCoxregres—sionanalysisshowedthatcoronaryarterydiseaseandstenosisofotherbloodvesselsweresignifi—cantIyrelatedwiththeprognosisofpatients(OR一8.893,95%CJ:2.885—27.418,P—O.OOO).C仰clusionPrognosisofsurvivedpatientswithsymptomat
7、icmiddlecerebralarteryocclusionisgood.Thefactorsinfluencingtheprognosisofpatientsarecoronaryarterydiseaseandstenosisofotherbloodvessels.Keywords:intracranialarteriosclerosis;brainischemia;coronarydisease;cerebralangiography;prognosis;riskfactors颅内动脉粥样硬化或闭塞足缺血性脑血管病发DOl:10.3969/
8、j.issn.10090126.2012.06.004基金项目:国家自然科学基金(30870848)作者单位:210002
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