实习九生存分析

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1、实习九生存分析一、目的要求1、掌握生存分析的基本概念：生存时间、生存率和中位生存期2、掌握生存曲线估计的Kaplan-Meier法和寿命表法3、熟悉生存曲线的特点及解释4、掌握生存曲线比较的log-rank检验的基本原理菜单:SPSS使用要点匡］生存分析・sag-SPSSDataEditorFileEditViewDataTransformJGraphsUtilitiesWindowHelp^lra

2、»l團出I日匚?12:肿瘤大小

3、生存时间1114211931264128512961327136814091421014411145121531315414159

4、15261627ReportsDescriptiveStatisticsTablesCompareMeansGeneralLinearModelMixedModelsCorreiateRegressionLoglinearClassify"taReductionScaleNonparametricTestsTimeSeriesSurvivalMultipleResponseMissingValueAnalysis・・・ComplexSamplesvarvarLifeTables...Kaplan~Meier..・CoxRegression.・・Coxw/Tim

5、e"DepCov.・・、Kaplan-M&er(P257,例16・1)1、数据结构2、分析方法：AnalyzeSurvival—Kaplan-Meier生存时间—►Time生存状态—►Status:DefineEvent肿瘤大小一►FactorCompareFactor：Kaplan-Meier:Co>pareFactorLevelsTestStatisticsVgogrank)厂Breslow厂Tarone-WareLineartrendforfactorlevels■ePooledoverstrata‘PairwiseoverstrataForeachst

6、ratum厂PairwiseforeachstratumContinueCancelHelpI3、结果:CaseProcessingSummary肿瘤大小TotalNNofEventsCensoredNPercent11411321.4%216160.0%Overall3027310.0%SurvivalTable肿瘤大小TimeStatusCumulativeProportionSurvivingattheTimeNofCumulativeEventsNofRemainingCasesEstimateStd.Error1114.0001.929.069113

7、219.0001.857.094212326.0001.786.110311428.0001.714.121410529.0001.643.12859632.0001.571.13268736.0001.500.13477840.0001.429.13286942.0001.357.128951044.0001.286.1211041145.0000•■1031253.0000■•1021354.0001.143.1181111459.0000■•110216.0001.938.06111527.0001.875.08321439.0001.813.09831

8、3410.0001.750.108412511.0001.688.116511612.0001.625.121610713.0001.563.12479820.0001.500.12588923.0001.438.124971025.0001.375.1211061127.0001.313.1161151230.0001.250.1081241334.0001.188.0981331437.0001.125.0831421543.0001.063.0611511650.0001.000.000160MeansandMediansforSurvivalTime肿

9、瘤大小Mean3MedianEstimateStd.Error95%ConfidenceIrdervalEstimateStd.Error95%ConfidenceIntervalLowerBoundUpperBoundLowerBoundUpperBound138.2863.76330.91045.66236.0007.48321.33350.667222.3133.41015.62828.99720.00010.000.40039.600Overall29.7132.86724.09235.33328.0002.73922.63233.368a・Estim

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