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1、ExtraWeightinEarlyChildhoodForetellsLaterDiseaseRiskAges2to6identifiedascriticalforpredictingproblemswithmetabolicsyndromeinadulthoodPosted:November22,2010ByJanetRaloff,ScienceNewsBabyfatcanbeaharbingerofseriousdiseaselateron.Beingoverweightasayoungchildisastrongpredictoro
2、fdiabetesandheartdiseaseriskinearlyadulthood,anewDutchstudyfinds.Previousresearchhaslinkedbeingoverweightinchildhoodwithahigherriskofthesechronicdiseasesinadulthood,butthenewstudyisthefirsttoidentifytheagesbetween2and6yearsasthemostimportantinpredictinglaterriskofmetabolic
3、syndrome,saysthestudy'sleadauthor,physicianMarloudeKroonofVUUniversityMedicalCenterinAmsterdam.Theconditionisassociatedwithincreasedriskoftype2diabetesandcardiovasculardiseases.Thenewwork"isveryinteresting,"sayscardiologistGeraldBerenson,becauseitrevealstheearliestandmostc
4、riticalageforpredictingadultweightproblemsandriskofseriouschronicdisease.Berenson,whowasnotinvolvedinthenewstudy,isdirectorofTulaneUniversity'sCenterforCardiovascularHealthinNewOrleans.Inthefaceofagrowingepidemicofchildhoodobesity,thesedataareverydisturbing,Berensonsays.Pe
5、opleoftendisregardchildren'sweightproblems,rationalizing"thatkidswillgrowoutofitduringpuberty,"hesays.Butthenewstudyshowsthatthekidsmaynot—andiftheydon't,bigproblemscouldensue.Toexploretherelationshipbetweenearlyweightgainandlaterdiseaserisk,researchersrepeatedlymeasuredth
6、eheightandweightof642Dutchchildrenbornbetween1977and1986inTerneuzen,theNetherlands.Fromthesemeasurements,scientistscalculatedtheyoungsters'body-massindex—orBMI,whichisameasureofheavinessthataccountsforheight—atleastonceayearfrombirththroughage18.ThentheyplottedhowBMIchange
7、dovertime.Later,asyoungadultsaged18to28,theparticipantsreturnedforfollow-upmeasurementsofwaistcircumference,fatundertheskinandbloodtests.IncreasingBMIbetweentheagesof2and6morethantripledtheriskthatayoungadultwouldexhibitsignsofmetabolicsyndrome,deKroonandhercolleaguesrepor
8、tinapaperpublishedonlineNovember12inPLoSOne.BMIincreasesbetweentheagesof10and18alsoposeda
