资源描述：
《@@Impact of ambiguity and risk on decision making in mild Alzheimer's disease》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、Neuropsychologia46(2008)20432055ImpactofambiguityandriskondecisionmakinginmildAlzheimersdiseaseH.Sinz∗,L.Zamarian,T.Benke,G.K.Wenning,M.DelazerClinicalDepartmentofNeurology,InnsbruckMedicalUniversity,Anichstrasse35,6020Innsbruck,AustriaReceived6Septe
2、mber2007;receivedinrevisedform30January2008;accepted1February2008Availableonline8February2008AbstractDecisionsunderambiguityanddecisionsunderriskarecrucialtypesofdecisionmakingindailylivingatanyage.Thisisthefirststudyassessingthesetwotypesofdecisionsi
3、npatientswithmilddementiaofAlzheimerstype(DAT)bymeansoftheIowaGamblingTask(IGT)andanewlydeveloped,Probability-AssociatedGambling(PAG)task.WhilerulesforgainsandlossesareimplicitintheIGT,inthePAGtaskrulesareexplicitandwinningprobabilities,whichchangefr
4、omtrialtotrial,canbeestimated.ResultsoftheIGTindicatedthatDATpatientsmademoredisadvantageousdecisionsthanhealthycontrols.Patientsalsoshiftedmorefrequentlyamongdecks,i.e.underambiguitydecisionsweretakenrandomlyandnoadvantageousstrategywasestablishedov
5、ertimebyDATpatients.Thus,notonlyactualchoicesbutalsodevelopmentofadvantageousstrategiesmayberevealingaboutdecisionmakingintheIGT.Comparedtocontrols,patientsdemonstratedlessadvantageouschoicesinthePAGtaskaswell.Theygambledmoreofteninthelowwinningproba
6、bilitiesandlessfrequentlyinthehighprobabilitiesthanhealthyparticipants.Patientsperformanceonbothtaskscorrelatedwithmeasuresofexecutivefunctions.Findingsofthepresentinvestigationareconsistentwiththeearlypathologicalcerebralchangesandrelated(cognitive,
7、emotional)deficitsreportedforDAT.Assuggestedbyourstudy,decisionsunderambiguityaswellasdecisionsunderriskareimpairedinmildDAT.ItmaythusbeexpectedthatpatientswithmildDAThavedifficultiesintakingdecisionsinevery-daylifesituations,bothincasesofambiguity(inf
8、ormationonprobabilityismissingorconflicting,andtheexpectedutilityofthedifferentoptionsisincalculable)andincasesofrisk(outcomescanbepredictedbywell-definedorestimableprobabilities).©2008ElsevierLtd.Allrightsreserved.Keywords:Decision;Risk;Ambiguity;DAT1
