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1、CaseA5-year-oldgirlThiefcomplain:vomited5timesfor3hours.Whathistoryofpresentillnessdoyouwanttoknow?2GASTRITISINCHILDRENDr.LiuChonghai4GastritisAcuteGastritisChronicGastritis5AcuteGastritis6FoodandDrugs:(NonsteroidalAntiinflammatoryDrugs,NSAIDs)Severestressstate:Acut
2、einfection:Corrosivesubstances:VagalstimulationAcidsecretionReleaseofvasoactiveamineandcytokinesMicrocirculationdisdurbanceGastricmucosalischemiaImpairmentofmucosalandmucousbarriersBack-diffusionofhydrogenionsShock,hydrocephalus,suddentrauma,seriousinfection,majorop
3、eration,etcAcutegastritisEtiology&Pathogenesis7ManifestationsAsuddenonsetTypicalmanifestations:epigastricpain,nausea,vomiting,waterydiarrheaFever:causedbybacterialinfectionoritstoxinsComplications:dehydration,electrolytedisturbances,acid-baseimbalance,UGIbleedingAcu
4、tegastritisManifestations8DiagnosisAcutesimplegastritisHistorysymptomsandsignsGIendoscopy&Biopsy(ifnecessary)AcutegastritisDiffusivehyperemiaandedemaofthegastricmucosaAcuteinflammation:neutrophilicinfiltrationinthelaminapropriaMayaccompaniedwithpunctatehemorrhageand
5、mildcorruptlesion9NormalGastricMucosaNGM10gastricmucosaledemaNGM11HemorrhagicgastritisHemorrhagicgastritiswithmultipleintramuralbleedingspotsNGM12A.RemoveofoffendingagentsQuitallirritantsorstimulus:drugs,alcoholManagementoftheoriginaldiseasesB.Symptomatictreatment1)
6、Replacementoffluidandelectrolyteloss2)Spasmolysant:Atropine,Belladonna4)Antiemeticdrugs:Domperidone3)SpecialmanagementforupperGIbleedingC.ProtectionofgastricmucosaandinhibitionofgastricacidMucosalprotectorAntacids:H2-RA,PPITreatmentAcutegastritis13Chronicgastritis14
7、Thetoptworeasonsforrecurrentabdominalpaininchildrenarechronicgastritis&PUDAnestimated10%schoolagechildrenisaffectedbyrecurrentabdominalpain.15Bydefinition,isahistopathologicalentitycharacterizedbychronicinflammationofthestomachmucosa.Itmaypresentwithanarrayofsymptom
8、s,themostcommonbeingnonspecificrecurrentabdominalpaininchildren.HighfrequencyinchildrenChronicgastritis16ClassificationNon-atrophic(Superf