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1、-798-２００8年9月中国医学物理学杂志Sep．,２００8第２5卷第5期ＣｈｉｎｅｓｅＪｏｕｒｎａｌｏｆＭｅｄｉｃａｌＰｈｙｓｉｃｓＶｏｌ．25．Ｎｏ．5影响调强放疗绝对剂量的主要因素及应对措施姜瑞瑶，熊霏，黄国锋，曹征，李兆斌，傅深（上海交大附属第六人民医院肿瘤放疗科，上海200233）摘要：目的：验证调强放射治疗的绝对剂量误差，探索影响调强放疗绝对剂量的因素及其应对措施。方法：将20例准备实施调强放疗病人的实际治疗计划，用标准水模体进行计划移植，生成验证计划并计算体模内电离室测量点的计划剂量，执行验证计划的照射，用电离室进行实际物理绝对剂量测量，
2、计算实际测量剂量值和计划剂量值的百分相对误差。分析影响调强放疗绝对剂量误差的主要因素，采取相应改进措施，验证另80例调强放疗的绝对剂量，比较前20例与改进后80例调强放疗绝对剂量验证结果。结果：前20例调强放疗绝对剂量百分相对误差分布范围是-8.00%~5.00%，平均误差为-2.01%，标准差为3.55%。采取相应改进措施后，80例调强放疗绝对剂量百分相对误差全部在4.4%以内，分布范围缩小到-4.4%~2.5%，平均误差为-1.49%，比前20例平均误差下降25.9%,标准差为1.40%，比前20例下降60.6%。结论：分析影响调强放疗绝对剂量的因
3、素，采取必要的应对措施，能够有效提高调强放射治疗绝对剂量的准确性。关键词：调强放射治疗；绝对剂量；验证中图分类号：R730.55文献标识码：A文章编号：1005-202X（2008）05-0798-03MainInfluentFactorsonAbsoluteDoseofIntensity-ModulatedRadiationTherapyandCountermeasuresJIANGRui-yao,XIONGFei,HUANGGuo-feng,CAOZheng,LIZhao-bin,FUShen（DepartmentofRadiationOncolo
4、gy,6thPeople,sHospital,JiaotongUniversity,Shanghai200233,China）Abstract:Objective:ToverifytheabsolutedoseaccuracyofIMRTandexploretheMaininfluentfactorsonabsolutedoseofintensity-modulatedradiatedtherapyandcountermeasures.Methods:Conductinghybridplansusingphantomgeometryand20cases
5、patient'sincidentbeamfluenceforIMRT.IrradiationdoseweremeasuredbyionizationchambertoverifytheabsolutedoseaccuracyofIMRT,calculatetherelativedifferencebetweenmeasureddoseandplanneddose.AnalyzingthemaininfluentfactorsonabsolutedoseofIMRTandtakingsomecountermeasures,verifytheabsolu
6、tedoseaccuracyofIMRTforanother80cases.Comparetheresultofabsolutedoseverificationbetweenthefirst20casesandtheimproving80cases.Results:Relativedifferencebetweenmeasureddoseandplanneddosearewithin-8.00%~5.00%forfirst20cases,averagedifferencewas-2.01%，standarddeviationwas3.55%.After
7、takesomeimprovingcountermeasures,relativedifferencebetweenmeasureddoseandplanneddosearewithin-4.4%~2.5%for80cases,averagedifferencewas-1.49%,decreased25.9%,standarddeviationwas1.40%,decreased60.6%.Conclusion:ItisefficienttoimprovetheabsolutedoseaccuracyofIMRTbyanalyzingthemainin
8、fluentfactorsonabsolutedoseofintensity-modulate
