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时间:2019-05-31
《09光动力疗法联合支架置入姑息性治疗癌性腔道梗阻 广州复大肿瘤医院论文之六十四》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、万方数据·论著·光动力疗法联合支架置人姑息性治疗癌性腔道梗阻——附26例报告牛立志周红桃曹斌摘要目的观察光动力疗法联合支架置入姑息性治疗恶性腔道梗阻的疗效及其并发症。方法26例腔道梗阻,失去手术机会或拒绝手术的中晚期癌症患者,包括15例食管癌、5例支气管癌,6例胆总管癌,行光动力疗法加支架置入姑息住解除腔道梗阻治疗。术后跟踪随访半年,观察疗效、并发症、KPS,定期内镜检查腔道通畅状况。结果26例患者,术后腔道梗阻明显缓解,仅l例食管癌患者发生支架移位,l例月嗵总管癌患者发生再次梗阻,KPS评分从平均31.O分提高至42.4分,并
2、发症经相应处理后均症状消失。结论光动力疗法联合支架置入姑息性治疗能有效缓解癌性腔道梗阻症状,并发症少,能明显改善腔道梗阻患者的生存质量。关键词光动力疗法;支架;癌症;梗阻中图分类号:R730.57文献标识码:A文章编号:1003—9430(2009)02—0088—04PhotodynamicTherapyCombinedwithStentImplantationforLuminaObstruc-tionCausedbyCancers·26CaseReportNlULi·zhi,ZHOUHong—tao,CAOBinGuangz
3、houFudaCancerHospital,Guangzhou510300ChinaABSTRACTObjectiveToobservethepalliativetherapeuticeffectsandcomplicationsofphotodynamictherapy(PDT)combinedwithstentimplan—tationonluminaobstructioncausedbycancers.MethodsTwenty.sixinoperableorrefusingsurgerylumina-obstructed
4、patients,including15esophagouscancer,5bronchialcarcinomaand6choledochuscancerpeteintsreceivedPDTcombinedwithstentimplantationinordertopalliativelyrelieveluminaobstruction.Pa—tientswerefoUoweduphalfayear,thetherapeuticeffects,complicationsandKamofskypointscale(KPS)wer
5、eobservedandrecordedandtheendoscopeexaminationwasperformedperiodicallytoobservetheluminaobstruction.ResultsAll26p娟即tssuccessfullyreceivedPDTandstentimplantationpalliativetherapy,hminaobstructionconditionwasob“ous—lyalleviated;of26patients,onlyonestentshiftedinesophag
6、eouscancerpatientandluminareobstructioninonecholedochnscancerpatientoccurred,theaverageKPSofpatientselevatedfrom31.0to42.4,allcomplicationswerehandledsafely.ConclusionsPDTcombinedwithstentimplantationpalliativetherapycKr',effectivelyalleviateluminaobstructioncausedby
7、cancerswithraremuchcomplications,andcannotablyimprovelifequality.{乍者单位:广州复大肿瘤医院(广州市,510300)作者简介:牛立志(1966一),男,陕西西安人,副教授,医学博士,主要从事肿瘤微创治疗临床研究工作。·88·万方数据KeywordsPhotodyanmictherapy;Stent;Cancer;Obstruction原发于腔道的恶性肿瘤如支气管癌、胆总管癌、食管癌和胃癌等,或源于其他组织转移到气管、胆管、食管的肿瘤,当肿瘤生长到一定体积时,会导致
8、上述腔道的梗阻,引发相应的临床症状,最终会导致患者营养不良、生存质量下降、生存期缩短。传统的手术治疗、无水乙醇注射及近距离放疗等在一定程度上能消除腔道梗阻,但因不良反应大或患者体质弱而不能施行上述治疗,因而对终末期失去上述治疗机会或拒绝上述治疗的患者,采取替代措
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