新型5-氟胞嘧啶与氟康唑杂合物的设计合成与抗真菌活性研究 (1)

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1、Contents中文摘要.....................................................................................................................IABSTRACT....................................................................................................................IV第一

2、章氟康唑类似物的研究新进展及论文选题........................................................1Chapter1Recentresearchesoffluconazoleanaloguesandstrategyofthisthesis..........11.1Introduction........................................................................................

3、........................................41.2Thereplacementoftriazolebyamines.......................................................................................51.2.1Aliphaticamines..........................................................................

4、...............................................51.2.2Alicyclicamines.......................................................................................................................101.2.3Otheramines.....................................................

5、........................................................................131.3ThereplacementoftriazolebyN-heterocyclesandfusedheterocycles...................................141.3.1N-heterocycles.................................................................

6、.........................................................141.3.2Fusedheterocycles....................................................................................................................191.4Thereplacementoftriazolebyethers........................

7、...............................................................211.5Thereplacementoftriazolebyothergroups............................................................................231.6Summary.................................................................

8、.................................................................241.7Strategyofthisthesis........................................................................................................