尼卡地平、艾司洛尔联合诱导期容量填充对静吸复合全身麻醉七氟醚用量的影响

《尼卡地平、艾司洛尔联合诱导期容量填充对静吸复合全身麻醉七氟醚用量的影响》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、}缶床麻醉学杂志2()(]9年9月第25卷第9期JClinAnesthesi01，september20¨09，V01．25，No．9·761·．临床研究．尼卡地平、艾司洛尔联合诱导期容量填充对静一吸复合全身麻醉七氟醚用量的影响张雷顾尔伟张颖徐光红陈立建张健【摘要】目的观察尼卡地平、艾司洛尔联合诱导期容量填充对静吸复合全身麻醉七氟醚用量的影响。方法6O例择期行脊柱手术的患者，随机均分为四组，诱导期以羟乙基淀粉1Oml／快速静滴行容量填充，诱导后插管前1min时分别静注艾司洛尔1mg／(E组)、尼卡地平2Og／(N组)、艾司洛尔1rng／复合尼卡地平20g／kg(EN组)或生理盐水(c组)，于

2、切皮前1min追加1／2首量药物或生理盐水。记录各组七氟醚用量、清醒、拔管时间及HR、MAP的变化。结果与C组比较，E组、N组及EN组术中所需七氟醚维持浓度均显著降低(P

3、icardipineO0mbiI州withVOl啪eexpaIIsiOnduringiIlducti0n0nseⅧl玎uraIlerequireIIlentduringintraven0usandinhalati0nalbaIancedaIIesthesiaZHⅣGL，GUEr_w，z4^／G，曙，efnf．Drfmenf0，An0fD罟y，开f伽口脚ff，An“MdicⅡf打v，H危f23O022，China【Abstract】0bjectiveToinvestigatetheeffectsofesmolo1，nicardipinecombinedwithvolumeexpansiondu

4、ringinductiononsevofluranerequirementduringintravenousandinhalatiomlba1ancedanesthesia．】ⅥethodsSixtypatientsundergoingspinalsurgerywererand0mlydividedinto4groupswith15caseseach．Al1patientsreceivedvolumeexpansionwithhydr0xyethylstarch1Oml／kgduringinduction．At1minbefOretrachealintubati0n，thepatientsw

5、eregivenabolusofesmol011mg／kg(groupE)，nicardipine2Og／kg(groupN)，esmolollmg／kgplusnicardipine2Og／kg(groupEN)ornomalsaline(groupC)，haifofwhichwasaddedatlminbeforeskinincisineinfourgroups．Sevofluranedosage，thetimeofconsci0usnessrecoveryandextubation，卜Ⅱand1V【APwererecorded．ResultsComparedwithgroupC，the

6、sevof1uranedosage，thetimeofconsciousnessrecoveryandextubationweresign

7、ficant1ylessingroupsofE，NandEN(P

8、mbinedwithvolumeexpansionduringinductionnotonlycanattenuatecardiovascu1arresponsetotrachealintubationandskinincision，butreducethesevofluranerequiementandshortenthetimeofconsciousnessrecoveryandextubationdur