自噬在雌激素缺乏骨质疏松小鼠骨髓间充质干细胞分化平衡中的作用研究

自噬在雌激素缺乏骨质疏松小鼠骨髓间充质干细胞分化平衡中的作用研究

ID:34964609

大小:3.65 MB

页数:72页

时间:2019-03-15

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1、分类号R780.2第四军医大学UDC616.7TheFourthMilitaryMedicalUniversity密级公开硕士学位论文自噬在雌激素缺乏骨质疏松小鼠骨髓间充质干细胞分化平衡中的作用研究戚朦培养类别全日制学位类型学术学位一级学科(专业类)口腔医学二级学科(专业)口腔基础医学研究方向干细胞与调控指导教师金岩教授(主任医师)培养单位口腔医院组织病理科二O一五年五月第四军医大学硕士学位论文目录缩略语表·················································

2、·············································1中文摘要······························································································2英文摘要······························································································7前言········

3、·····················································································13文献回顾·····························································································14正文··································································

4、···························22第一部分雌激素缺乏性骨质疏松小鼠骨髓充质干细胞自噬水平的变化··········221实验材料·····················································································222实验方法·····················································································2

5、43实验结果·····················································································314讨论···························································································31第二部分体外调节小鼠骨髓间充质干细胞自噬水平对其分化功能的影响·······331实验材料····················

6、·································································332实验方法·····················································································343实验结果·····················································································374讨论

7、···························································································39第三部分调节小鼠体内自噬水平对骨量及骨髓间充质干细胞分化功能影响····411实验材料·····················································································412实验方法··························

8、···························································413实验结果·····················································································454讨论··································································

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