糖尿病心脏自主神经病变早期检测方法的比较

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1、授予单位代码10089学号或中请号08010010063HebeiMedicalUniversity硕士学位论文专业学位糖尿病心脏自主神经病变早期检测方法的比较研究生：赵思楠导师：张力辉教授专业：内科学二级学院：第二医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。.本学位论文所获的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位主要内容相关的论文，第一署名单位为河北医科大学，试验材料、原始数据

2、、申报的专利等知识产权均归河北医科大学所有。否则，承担相应的法律责任。研究生签名导师签章：於"二级筆藓弩章：‘‘八V-.-'••—河北医科大学研宄生学位论文独创性声明本论文是在导师指导下进行的研宄工作及取得的研究成果，除了文中特别加以标注等内容外，文中不包含其他人己经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名：导师签章：^>(r年j月乂日目录中文摘要······························································

3、···································1英文摘要·································································································3英文缩写·································································································6研究论文糖尿病心脏自主神经病变早期检测方法

4、的比较前言·······························································································7材料与方法····················································································8结果····································································

5、···························9附表·······························································································10讨论·······························································································11结论·································

6、······························································13参考文献························································································13综述糖尿病心脏自主神经病变的临床意义、评估、诊断与治疗···········17致谢·····························································

7、·········································29个人简历·······························································································30中文摘要糖尿病心脏自主神经病变早期检测方法的比较摘要目的：糖尿病患病率与日俱增，而糖尿病神经病变是糖尿病常见的慢性并发症，其中自主神经病变发病率约为60%。糖尿病心脏自主神经病变（Diabeticcardiovascularauton

8、omicneuropathy,DCAN）指因糖尿病引起支配心脏血管自主神经系统（交感神经与副交感神经）病变，引起心率异常、血管舒缩功能紊乱等。可表现为心率增快并固定、血管调节受损，如体位性低血压，出现无痛性心肌梗塞，甚至出现心脏骤停而猝死。目前用于评估糖尿病心血管自主神经功能的检查方法主要有心血管反射试验（Ewing法）以及心率变异性（Hear