益气温阳法治疗糖尿病心脏自主神经病变的临床观察

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1、提要目的：观察采用益气温阳法（生脉散合桂枝甘草龙骨牡蛎汤加减）治疗糖尿病心脏自主神经病变在临床上的疗效，以及对患者心率变异性的影响，并初步探讨其作用机制。方法：将确诊为糖尿病心脏自主神经病变的60例患者，随机分为两组，每组各30例。治疗组和对照组在基础降糖治疗的同时，分别予以自拟方和西药弥可保，共治疗12个周。分别观察两组患者治疗前后临床症状、空腹血糖、餐后2h血糖、糖化血红蛋白、心率变异性等指标的变化，并进行对比分析。结果：治疗后，治疗组总有效率为93.3％，对照组总有效率为66.7％，两组经统计学处理，有显著意义（p＜0.05）。治疗组在改善患者临床症状，降

2、低血糖，提高心率变异性方面较对照组有明显优势，临床观察期间未发现明显不良反应。结论：采用益气温阳法治疗糖尿病心脏自主神经病变有显著的临床疗效，可明显提高心率变异性，改善自主神经功能。关键词糖尿病心脏自主神经病变；心率变异性；益气温阳法；弥可保TheClinicalObservationofReplenishingQi,WarmingYangTherapyonDiabeticCardiacAutonomicNeuropathySpeciality：InternalmedicineofTCMAuthor：XuChunfangTutor：Professor.YangW

3、enjunAbstractObjective:ToobservetheclinicaleffectofreplenishingQi,warmingYangtherapy（self-makedchinesedecoction）ontreatingdiabeticcardiacautonomicneuropathyinpatientswithheartratevariability.Andpreliminarydiscussionmechanism.Methods:60patientswithdiabeticcardiacautonomicneuropathywer

4、edividedrandomlyintotwogroups(n=30).TheexperimentgroupweretreatedwithHypoglycemicDrugsorinsulinandSelf-makedChineseDecoction,withatotalcourseoftreatmentfor12weeks.ThecontrolgroupweretreatedwithHypoglycemicDrugs,insulinandMethycobal,observedinclinicalsymptomchanges,thebloodglucose,gly

5、catedhemoglobin,bloodrheology,heartratevariabilityindex,beforeandaftertreatment.Result:Aftertreatment,effectivepowerinexperimentgroupis93.3%,and66.7%incontrolgroup.thedifferenceswasstaticallysignificant(P<0.05).Conclusion:ReplenishingQi,warmingYangtherapyondiabeticcardiacautonomicneu

6、ropathyhassignificanteffectandcanimproveheartvariability.KeywordsDiabeticcardiacautonomicneuropathy;Heartratevariability；ReplenishingQi,WarmingYangTherapy;Methycobal目录引言...................................................................................................................

7、............1临床研究...............................................................................................................................2一、临床资料.......................................................................................................................2（一）病例来源......

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