术前小剂量奥曲肽在预防ercp术后胰腺炎和高淀粉酶血症中的应用研究

《术前小剂量奥曲肽在预防ercp术后胰腺炎和高淀粉酶血症中的应用研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号13282HebeiMedicalUniversity硕士学位论文在职科学学位术前小剂量奥曲肽在预防ERCP术后胰腺炎和高淀粉酶血症中的应用研究学位申请人：王菲导师：刘科霞教授专业：外科学二级学院：沧州市中心医院2015年3月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师(或指导小组)的指导下，由本人独立完成。本学位论文研究所获得的研究成果,其知识产权归河北医科大学所有《>河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医科大学，

2、试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则,承担相应法律责任。、、/务1V'研究生签名：_导师签章力

3、^(减N��曰河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果,除了文中特别加以标注和致谢等内容外,文中不包含其他人已经发表或撰写的研究成果,指导教师对此进行了审定。$论文由本人独立撰写,文责自负。、研究生签名：*导师签章：&年劣月乂日目录中文摘要·······························································

4、··············1英文摘要·············································································3英文缩写·············································································6研究论文术前小剂量奥曲肽在预防ERCP术后胰腺炎和高淀粉酶血症中的应用研究前言····················································

5、·························7材料与方法····································································8结果·············································································10附表·············································································14讨论······

6、·······································································22结论·············································································27参考文献·······································································27综述经内镜逆行性胰胆管造影术后胰腺炎的预防现状················

7、·30致谢···················································································40个人简历·············································································41中文摘要术前小剂量奥曲肽在预防ERCP术后胰腺炎和高淀粉酶血症中的应用研究摘要目的：观察术前应用小剂量奥曲肽预防经内镜逆行胰胆管造影术（endoscopicretrogradecholangio

8、pancreatography,ERCP）术后胰腺炎（Post-ERCPPancreatitis,PEP）和高淀粉酶血症的疗效，评价小剂量奥曲肽在ERCP术前应用的临床价值，为临床ERCP术前预防性用药提供依据。方法：制定严格的纳入与排除标准，收集自2011年8月至2014年12月期间在沧州市中心医院普外科行ERCP治疗且符合条件的553例患者资料为研究对象，包括男性308例，女性245例，年龄31～88（67.5±11.5）岁，其中胆管结石280例，胆管癌126例，胰头癌89例，壶腹癌31例，十二指肠乳头癌23例，十二指肠乳头炎性狭

9、窄4例。记录所有患者术前1d、术后6h、24h血清淀粉酶，术后患者有无腹痛、恶心呕吐、发热、上腹部压痛等临床表现，确诊为PEP的患者通过CT检查结果判断轻重程度。根据术前0.5h是否应用小剂量奥曲肽（0.1mg）将研究对