儿童炎症性疾病早期诊断指标超敏c反应蛋白、降钙素原和白细胞计数的比较

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1、授予单位代码10089学号或申请号20123052HebeiMedicalUniversity硕士学位论文专业学位儿童炎症性疾病早期诊断指标超敏C反应蛋白、降钙素原和白细胞计数的比较作者姓名：封丽洁导师：张会丰教授陈源副教授专业：儿科学二级学院：第二医院2015年03月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研究所获得的研究成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公幵和使用。凡发表与学位论文主要内容相关的论文，第一署名为单位河北医

2、科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。研究生签名师签二级学院领导盖章:年1月初日河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研究工作及取得的研究成果，除了文中特别加以标注和致谢等内容外，文中不包含其他人已经发表或撰写的研究成果，指导教师对此进行了审定。本论文由本人独立撰写，文责自负。研究生签名导师签章⑶JT年？月W曰目录中文摘要····································································

3、··········1英文摘要··············································································5英文缩写··············································································9研究论文儿童炎症性疾病早期诊断指标超敏C反应蛋白、降钙素原和白细胞计数的比较前言·····················································

4、·························10材料与方法·····································································11结果·············································································14附表·············································································16讨论···

5、··········································································21结论·············································································26参考文献·······································································27综述炎症标志物的研究进展························

6、··························30致谢···················································································40个人简历·············································································41中文摘要儿童炎症性疾病早期诊断指标超敏C反应蛋白、降钙素原和白细胞计数的比较摘要目的：比较脓毒症、呼吸道感染感染、过敏性紫癜和病毒性脑炎等疾病时

7、，超敏C反应蛋白（hs-CRP）、降钙素原（PCT）和白细胞计数（WBC）的变化特点及相互关系，探讨超敏C反应蛋白（hs-CRP）、降钙素原（PCT）、白细胞（WBC）在儿童炎症性疾病早期诊断的意义，为临床合理用药提供依据。方法：研究对象为2014年3月至2015年3月期间，在河北医科大学第二医院小儿内科住院80例炎症性疾病患儿进行分组。本研究将所有研究对象按疾病类别分为4组：脓毒症组，下呼吸道感染感染组，过敏性紫癜组，病毒性脑炎组。脓毒症组患儿20例，其中脓毒症患儿16例，MODS4例；下呼吸道感染组20例，其中肺炎15例，支气管炎

8、5例；过敏性紫癜组，20例；病毒性脑炎组，20例。所有研究对象均于住院当日或次日，采取末梢血检测超敏C-反应蛋白（hs-CRP）。同时抽取静脉血3ml进行降钙素原（PCT）和白细胞检测。比较以上不同疾病状况各指标检测结果