mir-200c和mir-141在胃癌中表达、功能及其调节机制的研究

《mir-200c和mir-141在胃癌中表达、功能及其调节机制的研究》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、授予单位代码10089学号或申请号20121073HebeiMedicalUniversity博士学位论文科学学位miR-200c和miR-141在胃癌中表达、功能及其调节机制的研究研究生：周欣亮导师：刘巍教授单保恩教授专业：肿瘤学二级学院：第四医院2015年4月河北医科大学学位论文使用授权及知识产权归属承诺本学位论文在导师（或指导小组）的指导下，由本人独立完成。本学位论文研宄所获得的研宄成果，其知识产权归河北医科大学所有。河北医科大学有权对本学位论文进行交流、公开和使用。凡发表与学位论文主要内容相关的论文，第一署名

2、为单位河北医科大学，试验材料、原始数据、申报的专利等知识产权均归河北医科大学所有。否则，承担相应法律责任。-研宄生签名导师签章：级学院领导盖章:年月y河北医科大学研究生学位论文独创性声明本论文是在导师指导下进行的研宄工作及取得的研宄成果，除了文中特别加以标注和致辨等内容外，文中不包含其他人己经发表或撰写的研宄成果，指导教师对此进行了审定。本论文由本人独立撰写，文责白负。L‘,研究生签名:摩么导师签章：年^JB目录中文摘要················································

3、·····························1英文摘要·············································································9英文缩写·············································································17研究论文miR-200c和miR-141在胃癌中表达、功能及其调节机制的研究引言··························

4、···················································18第一部分miR-200家族在胃癌组织和细胞系中的表达及其与临床病理特征和DFS的关系前言·············································································20材料与方法····································································21结果········

5、·····································································27附图·············································································30附表·············································································39讨论··························

6、···················································42小结·············································································45参考文献·······································································45第二部分miR-200c和miR-141对胃癌细胞生物学行为的影响及其机制研究前言·········

7、····································································52材料与方法····································································53结果·············································································67附图·································

8、············································71附表·············································································83讨论············································