弓形虫营养缺陷型毒株的构建及其免疫保护作用研究

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1、分类号密级HUAZHONGAGRICULTURALUNIVERSITY硕士学位论文MASTER’SDEGREEDISSERTATION弓形虫营养缺陷型毒株的构建及其免疫保护作用研究CONSTRUCTIONOFTOXOPLASMAGONDIIAUXOTROPHICSTRAINSANDSTUDYOFTHEIRIMMUNOPROTECTIONEFFICACY研究生:周太芳CANDIDATE：ZHOUTAIFANG学号:2016302120092STUDENTNO.：专业:兽医硕士MAJOR：MASTEROFPROFESSIONALDEGREEINVETERINARYMEDICINE导师:申邦教

2、授SUPERVISOR：PROFESSORSHENBANG王波林兽医师VETERINARIANWANGBOLIN中国武汉WUHAN，CHINA二0一八年六月June，2018华中农业大学硕士学位论文弓形虫营养缺陷型毒株的构建及其免疫保护作用研究ConstructionofToxoplasmagondiiAuxotrophicStrainsandStudyoftheirImmunoprotectionEfficacy研究生:周太芳学号:2016302120092指导教师:申邦教授王波林兽医师学位类型:兽医硕士领域：华中农业大学动物医学院中国·武汉CollegeofVeterinaryMed

3、icine,HuazhongAgriculturalUniversityWuhan,China2分类号密级本课题来源于新进高层次人才科研项目：弓形虫缓殖子形成的分子机制(项目编号：2015RC001)，感谢该项目对本课题的经费支持！弓形虫营养缺陷型毒株的构建及其免疫保护作用研究目录目录......................................................................................................................................I摘要.................

4、.....................................................................................................................iAbstract...............................................................................................................................iii1前言......................................

5、...........................................................................................11.1研究问题的由来.......................................................................................................11.1.1弓形虫及弓形虫病..............................................................................

6、..............11.1.2弓形虫的嘧啶合成............................................................................................31.2弓形虫疫苗的研究进展...........................................................................................41.2.1灭活疫苗..............................................................

7、..............................................51.2.2疫苗抗原候选分子研究....................................................................................61.2.3活疫苗...............................................................