子宫内膜淋巴结转移相关因素分析

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1、答辩委员会主席：奎继丞塾拯逝江太堂医堂院答辩委员会成员：垣题教援湿丛医堂院论文答辩日期：2O13年5月26日温州医学院硕士学位论文目录IIIIIIIIIIIIIqllllLLIIlllllIIIY2397576缩略语词表······································3中文摘要····································4英文摘要···································6引言························

2、············8材料与方法································9结果······································12一般资料···································12统计学分析···································15讨论······································18一般状况分析································

3、···18淋巴结转移······································19淋巴结转移相关······································19手术方式选择······································20小结·····································23参考文献······································24附录··························

4、·······411····27致谢······································28综j苤······································29独创性申明······································33简写ECCCCFIGOCAl25UPSCCCCPLNPLANERPRBMINCCN温州医学院硕士学位论文英文缩略词表EndometrialcarcinomaClearcel1carcinomaInternationalF

5、ederationofGynecologyAndObstetricsCancerantigenl25中文子宫内膜癌透明细胞癌国际妇产科联盟糖类抗原125Uterinepapillaryserouscarcinoma浆液性乳头状腺癌ClearcellcarcinomaPelviclymphnodeParaaorticlymphnodeestrogenreceptorProgesteronereceptorBodymassindex透明细胞癌盆腔淋巴结腹主动脉旁淋巴结雌激素受体孕激素受体体重指数National

6、ComprehensiveCancer美国国立综合癌症网络Network温州医学院硕士学位论文子宫内膜癌淋巴结转移相关因素分析中文摘要目的通过回顾性分析温州医学院附属第一医院妇科手术治疗的子宫内膜癌病例96例，对其临床、病理、手术方式等资料进行回顾，对淋巴结转移的相关因素进行分析，以明确淋巴结转移的潜在危险因素，为早期患者的手术方式选择提供参考。方法收集2007年3月至2012年3月于温州医学院附属第一医院住院手术治疗且术后组织病理确诊为子宫内膜癌病例96例。将患者的一般情况、病史、辅助检查、治疗、病理资料

7、等记录筛选后建立数据库，对其临床、病理及手术方式等进行回顾性分析，研究并探讨不同病理类型、组织学分期、肌层浸润深度、腹水细胞学及宫外转移等因素与淋巴结转移的关系，以助于早期子宫内膜癌患者合理选择手术方式。应用SPSSl8．0软件进行统计学分析，单因素分析采用卡方检验和Fish确切概率法，多因素分析采用Logistic回归模型。结果：1．96例子宫内膜癌患者发病年龄介于22岁～78岁之间，平均年龄53．4±1．7岁，50—59岁发病人数最多，共53例，占55．2％；已绝经者60例，占62．5％。患者临床症状主

8、要为不规则阴道流血者84例，占87．5％，包括未绝经者29例，已绝经者55例，术前依靠多种辅助检查及诊刮病理确诊。2．96例子宫内膜癌患者均行手术治疗，手术方式各不相同，术后按照国际妇产联盟(FIGO)2009年标准行手术一病理分期：I期：60例；II期：16例；ⅡI期：17例；Ⅳ期：3例。3．术后组织病理学结果显示96例子宫内膜癌病理类型以腺癌为主共92例，占95．8％，特殊病理类型子宫内膜癌4例。组织学分期：