2型糖尿病患者心率变异性与微血管并发症的相关性及氧化应激对心率变异性的影响

《2型糖尿病患者心率变异性与微血管并发症的相关性及氧化应激对心率变异性的影响》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、万方数据天津医科大学硕士学位论文contr01．Theage、BMI、waistclrcuInf．efence、waist—hipratio、SBP、DBP、hypertensiondiseasehistory，coronaryheartdiseasehistory、HbAlc、TG，TC、LDL-C、8-iso—PGF2aofT2DMpatientsweresignificantlyhigherthanthehealthycontrol；andSDNN、SDANN、SDNNIDX，rMSSD、pNN50、LF、HFlVLF，LF／HF、SODweresignificantlylowe

2、rthanthehealthycontr01．(2)TheSDNN、SDANN、SDNNIDX、rMSSD、pNN50、LF、HF、LF／HFofDPN(+)groupweresignificantlylowerthanDPN(一)patients；whereas8-iso—PGF2awashigher．(3)Compared谢t11theDN(-)group，theSDNN、SDANN、SDNNIDXofDN(+)groupweresignificantlyreduced；(4)Compared淅mtheDR(一)group，theSDNN、SDANN、SDNNIDX、rMSSD、p

3、NN50、VLF、LF／HFofDR(+)patientsweresignificantlyreduced．(5)Moreelevatedtheserum8-iso—PGF2levels，moredecreasedtheSDNN、SDANN、SDNNIDX，rMSSD、pNN50，VLF；(6)MoreelevatedserumlevelsofSODactivity,moreincreasedtheSDNN，SDANN，SDNNIDX，rMSSD，pNN50，LFandVLF．Conclusions：(1)Compared淅thnormalsubjects，HRVofpatientsw

4、ithtype2diabetesreducedsignificantly,theoxidationfactor8-iso·PGF2aiNGTreasedobviously，theantioxidantfactorSODdecreased；(2)HRVofdiabetesmellituspatients、析tllperipheralneuropathy．diabeticnephropathyandretinopathyweremuchlowerthanthatofT2DM；(3)Along、历tlltheelevatedlevelofanti-oxidantfactorSODanddec

5、reasedlevelofoxidationfactor8-iso．PGF2a,HRVgraduallyinereased．Keywords：type2diabetesmellitusmicrovascularcomplicationscardiovascularautonomicneuropathy8·iso—prostaglandinF2asuperoxidedimutaseIV万方数据天津医科大学硕士学位论文目录中文摘要⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯IAbstract⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．

6、III缩略语／符号说明⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯VII前言⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．1日U百⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．研究现状、成果⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯1研究目的、方法⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯3对象和方法⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯41．1研究对象⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．41．2诊断标准⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯

7、⋯⋯⋯⋯⋯⋯⋯41．2．1T2DM⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．41．2．2糖尿病周围神经病变(DPN)⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯41．2．3糖尿病肾病(DN)⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．41．2．4视网膜病变(DR)⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．41．3研究方法⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯．．51．3．1一般资料收集⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯⋯