脑电双频指数在儿科icu镇静监测的应用研究

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1、上海交通大学硕士毕业论文±4.97、49.72±6.00；Spearman’等级相关分析，BIS与Ramsay评分的相关系数为-0.8879，具有高度相关性（P<0．01）。提取6月～1岁患儿数据分析，BIS与Ramsay评分的相关系数为r=-0.8427，无明显的相关性（P＞0．05）。结论BIS监测操作简单、经济方便。BIS范围在55-80之间为儿童危重病患儿合适的镇静分值。BIS与Ramsay评分在危重病镇静深度评估中具有较好互补性。BIS监测可作为儿童危重病镇静判断的客观指标。关键词:危重病，脑电双频指数，Ramsay评分，咪唑安定，儿童-2-上海交通大学硕士毕业论文BISPEC

2、TRALINDEXAPPLIEDTOSEDATIONFORPATIENTSINPAEDIATRICSINTENSIVECAREUNITABSTRACTOBJECTICV:Discussingtheapplicabilityofbispectralindex（BIS）usedinmonitoringsedativesinpaediatricsintensivecareunit.METHODS:prospectivestudy.42patientsinPICUofourhospital,whichwereneededtobesedatedfortheillnessandrescuing,we

3、regivenMidazolambycontinuouslyintravenousinjection.KeepingthepatientscalmandtheScoreofRamsaybetween3and5pointweresuitableextent.RecordingthesedativedepthaccordingtotheScoreofRamsay,simultaneouslyrecordingthevalueofBIS.AnalyzingtherelationshipbetweenRamsayscoreandBISvalueandthefactorsinfluencedBIS

4、.RESULTS:42criticallyi11childreninPICUofShanghaiJiaotongUniversityaffiliatedchildrenhospitalfromJune2007toMarch2008。Including13casesthatagewasform6monto1year.24boycases-3-上海交通大学硕士毕业论文（57.14%），18girlcases（42.86%），themeanagewas21.23±5.56mon(6mon-13yrs).Theobjectsshouldremovethesecases:Cerebralpalsy

5、、cerebraldevelopmentalretardation、mentalretardation、epilepsy、scalpedema、Intracalmasses、haematomaetc.AfterapplyingMidazolampatientsbegantoproduceamarkedeffectandBISbegantochange3-5minutes.sowhentheRamsayscorewere2,3,4,5,6,thecorrespondingvalueofBISwere84.66±4.68、79.89±5.27、64.65±5.13、55.80±4.97、49

6、.72±6.00；accordingtoSpearman’sscaleanalysis,thecorrelationcoefficientofBISandRamsayscoreis-0.8879（P<0．01）,whichhasevidentlystatisticalsignificance.Thecorrelationcoefficientoflittlechildrenteam(agefrom6monto1year)was-0.8427,noevidentlystatisticalsignificance（P＞0．05）.CONCLUSION:BISisanobjectivemeth

7、odonsedativemonitoringforPICUpatients.Betterexercisablesandeasily.BISwasaproperrangeforsedativedepthwhentheBISvalueisinrange60-80.BISusedinsedativemonitoringhadcomplementarilywithRamsayscore.KEYWORDS:criticallyi11,bisp