中药综合治疗2型糖尿病足早期下肢血管病变的临床观察

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1、要目的：观察中药综合治疗对老年2型糖尿病足（早期）下肢血管病变相关因素旳影响。方法：选择符合标准的糖尿病足(早期)患者90例，采用随机单盲对照方法分为综合治疗组60例和对照组30例，综合治疗组在一般治疗的基础上给予中药内服加外洗；对照组给予一般治疗，治疗8周，观察治疗前后症状、血糖、血脂、凝血系列、血流变学、内皮四项、下肢动静脉彩超、踝/助:指数等指标，并釆用SPSS17.0统计软件进行数据处理。结果：综合治疗组总有效率分别为86.7%、83.3%,与对照组有效率63.3%相比,均有显著性差异(P<0.05)，提示中药综合治疗可以明显改善老年2型糖尿病早期下肢血管

2、病变的临床症状，同时治疗组的血脂、凝血系列、血流变学、内皮四项、下肢动静脉彩超、躁/肱指数等指标，均较前明显改善，与对照组比较有显著性差异(P<0.05)。结论：中药综合治疗通过调节病人的糖脂代谢紊乱，改善凝血系列、血流变、内皮四项、踝/肱指数、下肢动静脉彩超指标等多靶点治疗，改善微循环，达到改善患肢局部供血，缓解或消除临床不适症状，从而降低糖尿病足坏疽的发病率和截肢率，提高患者的生活质量，符合中医理论“未病先防，既病防变”的原则。关键词中药综合治疗；2型糖尿病足早期下肢血管病变；益气活血；化痰通络;临床研究TraditionalChinesemedicinemu

3、lti-modalitytype2diabetesmellituslowerlimbbloodvessellesionSpeciality:InternalMedicineofTCMAuthor:CaoXiang-lingTutor:Pro.CuiDe-zhiAbstractObjective:toobservetheeffectofComprehensiveTraditionalChinesemedicinetreatmentontype2diabeticfoot(early)vascularlesionsinthelowerextremitiesandrela

4、tedfactors.Methods:inaccordancewiththestandardsofthediabeticfoot(early)in90patients,usingarandomizedcontrolledsingleblindmethodisintegratedintothetreatmentgroup60casesandcontrolgroup30cases,comprehensivetreatmentofthetreatmentgroupwasgivenbasedonthetraditionalChinesemedicineandexterna

5、lwashing;thecontrolgroupreceivedgeneraltreatment,after8weeksoftreatment,observationofsymptomsbeforeandaftertreatment,bloodglucose,bloodlipid,bloodrheology,endothelialfourindex,lowerextremityarteriovenouscolorindex,ankle-brachialindex,andusingSPSS17.0statisticalsoftwarefordataprocessin

6、g.Results:thecombinedtreatmentgrouptotaleffectivenessrespectivelyis86.7%,83.3%，andeffectiverateofcontrolgroupcomparedto63.3%,thereweresignificantdifferences(P<0.05),theprompttraditionalChinesemedicinecomprehensivetherapycansignificantlyimprovetheelderlytype2diabeticpatientswithearlydi

7、abeticlowerextremityarterialdiseaseclinicalsymptoms,whilethetreatmentgroupoflipids，bloodrheology，endothelinfourindex,lowerextremityarteriovenouscolorindex,ankle-brachialindex,weresignificantlyimproved,comparedwiththecontrolgroupwithsignificantdifference(P<0.05)Conclusion:TraditionalCh

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