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1、结论应用不同修复材料治疗牙槽突裂，通过影像学和组织学检测，观察上颌骨发育情况及局部成骨能力，相互对比，证实各种材料植入牙槽突裂隙内，（1）对上颌骨发育有不同程度的影响：其中自体髂骨影响最小，脱钙骨次之，骨水泥影响最大；（2）从成骨能力上看，从好到差依次为：髂骨组，脱钙骨组，骨水泥组，髂骨组明显优于其他各组。关键词自体髂骨脱钙骨骨水泥CT三维重建牙槽突裂2TheexperimentalstudyonbonereconstructionofalveolarcleftbydifferentmaterialsAbstractObject:Establis
2、hrabbit’smodelofunilateralalveolarcleft,discusstheeffectofmaxillarygrowthfurtheranddevelopmentandcomparetherespectiveosteogeniccapabilitytoregeneratealveolarcleftwhichusedautogenousiliacbone,puredecalcifiedbonematerialandacryliccement.Method:(1)choose40NewZealandwhiterabbits(
3、8weeksold,1~1.2kg.)assamplesandresultintheirunilateralalveolarcleftthroughoperation;(2)these40rabbitswereaveragelydividedinto4groupsrandomly:iliacbonegroup,decalcifiedbonegroup,acryliccementgroupandblankgroup2weeksafteroperation.Theotherthreegroupsareimplantedautogenousiliacb
4、one,,puredecalcifiedbonematerialandacryliccementintothedefectsrespectivelyexceptthattheblankgroupwassubjectedtonodisposal;(3)observetheirskullsbythree-dimensionalCTafter2weeks,4weeks,6weeksand8weeksrespectivelyandmeasurethedistancebetweensuturesofmaxillary,moreover,obtaintheC
5、Tnumberstomasterthedevelopmentofmaxillary.2rabbitsineachgroupweresacrificedtoobtaintheirtissuesamplesandobservethemtomastertheinformationofosteogeniccapability.Weconductpairedt-testanalysisonthedataofthehealthysidesandsicksidesbyapplyingSPSS19.0softwareandconductone-wayanalys
6、isofvariance(LSD)tothedataofdifferentgroups.Inaddition,comparethedifferenceofeffectofmaxillarygrowthanddevelopmentandosteogeniccapabilitybetweentestgroupsandblankgroup.Results:2,4,6and8weeksafteroperation:(1)wecanseethateffectonmaxillarydevelopmentvariesaccordingtodifferentte
7、stgroups,①wecanseethatPareallgreaterthan0.05bycomparingthewidthandheightofmaxillary,sothese3datahavenostatisticalsignificance;②comparetheskewnessofsnoutwefindthatPinacryliccementgrouparesmallerthan0.05,sothisdatahasstatisticalsignificance,butPinotherthreegroupsareallgreaterth
8、an0.05bypairwisecomparison,sothesedatahavenostatisticalsignificance.
