特发性间质性肺炎与结缔组织病相关性间质性肺疾病比较分析

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1、万方数据英文摘要Acomparativestudyonidiopathicinterstitialpneumoniaandconnectivetissuedisease．associatedinterstitiallungdiseasesABSTRACTobjective：Toanalyzeandcomparetheclinicalmanifestations，laboratoryfindings，high—resolutioncomputedtomography(职CT)findingsandtreatmentofidiopathicint

2、erstitialpneumonia(IIP、》withconnectivetissuedisease．associatedinterstitiallungdiseases(CTD—ILD)。theultimategoaliStoQjveevidelfodistinguishingthetwodifferentdiseasessomeevidencetorthetwomtterentalseases．91vedlstlngulsnlng·Methods：PatientswithIIPorCTD—ILDfromrespiratorydepart

3、mentintheeasterndistrictoftheSecondHospitalofHeBeiMedicalUniversity,fromFebruary，2013toDecember,2014wereselectedinthisstudy．Theclinicalfeatures，laboratoryfindings，职CTfindingsandtreatmentwereanalyzedandcomparedbetweenthetwogroups．Results：Atotalof87patientswithcompletedatawer

4、eincludedinthisstudy,with58IIPcasesand29CTD—IL，Dcases．CTD-ILDiScommoninmanyofthesediffuseconnectivetissuediseases，includingRheumatoidArthritis(RA)，SystemicLupusErythematosus(SLE)，Sjogren’Ssyndrome(SS)，Systemicsclerosis(SSc)，PolymyositisandDermatomyositis(PM／DM)．IIPgroup：32m

5、alesand26female．hadanaverageageof(70．O±1O．8)years，therewere30smokers．CTD—ILDgroup：10malesand19female，hadanaverageageof(60．1±12．0)years，therewere7smokers．Age，gender,smokinghistoryshowedsignificantlydifferencebetweenIIPandCTD—ILDgroup(P<0．05)．ClinicalManifestations：mainsympto

6、mswerecough，sputumproduction，chestdiscomfort，dyspnea，andcracks，whichmoreIIPpatientssuffers．Ⅵmilechestdiscomfort，dyspnea，fingerclubbingandsymotomsrelatedtoCTDsuchasskinrash，arthralgia，Raynaud’SphenomenonandSOon，showedsignificantdifferencesbetweenIIPandCTD—ILD(P<0．05)．Serolog

7、ictests：SignificantdifferenceinserologictestsbetweenCTD—ILDgroupandliPgroupwasseeninautoantibodiesseries(ANA，egP,Anti—Smith，Anti—SSA，4万方数据英文摘要—————————————————————————————————————————————————————一——————————————————————————————————————一Anti—SSB，Anti—Scl．70，Anti—Jo．1，㈣Anti—ds

8、—DNA)，RF,Anti—CCP,ANCA，IgM，C3，C4妒