雷公藤多甙片联合益肾蠲痹丸治疗类风湿关节炎的疗效评价

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1、提要目的：通过临床观察评价雷公藤多甙片联合益肾蠲痹丸治疗类风湿关节炎肾虚血瘀证的临床疗效。方法：选择2010年4月～2011年4月就诊于山东中医药大学附属医院风湿科门诊及住院患者。将符合纳入标准的80例患者随机分为试验组40例和对照组40例，试验组服用雷公藤多甙片和益肾蠲痹丸，对照组服用甲氨喋呤和柳氮磺吡啶片，两组治疗时间均为24周，观察两组的关节压痛个数、关节肿胀个数、晨僵时间、血沉（ESR）、C反应蛋白（CRP）等指标的变化，以及临床疗效比较。结果：试验组能明显改善患者症状，对临床症状、实验室检查、中医

2、证候的改善明显优于对照组。结论：雷公藤多甙片联合益肾蠲痹丸能明显改善患者病情，治疗效果优于甲氨喋呤与柳氮磺吡啶片。关键词关节炎，类风湿，雷公藤多甙片，益肾蠲痹丸，临床疗效。TripterygiumwilfordiimuchglucosidepiecesandbenefitingkidneyJuanbipillcertifiedsharetreatmentevaluationofclinicalcurativeeffectofrheumatoidarthritisSpeciality：InternalMedi

3、cineofT.C.MRheumaticDiseasAuthor：SunQianTutor：Professor.SunSuPingAbstractObjective:ToobservetheclinicalevaluationtripterygiumwilfordiimuchglucosidepiecesandbenefitingkidneyJuanbipillcertifiedsharetreatmentrheumatoidarthritiskidneybloodstasissyndromeofclini

4、calcurativeeffect.Method:ChooseinApril2010toApril2011clinicinShandonguniversityofTraditionalChineseMedicinehospitalRheumatismDepartmentoutpatientandinpatient.Willmeetthecriteria80caseswererandomlydividedintothetestgroup(40cases)andcontrolgroup(40cases),pat

5、ientstripterygiumwilfordiiofmoreglucosideandbenefitingkidneyJuanbipill,thecontrolgrouptakingmethotrexateandliunitrogenofsulfonylureapyridine,twogroupsoftreatmenttimefor24weeksareobserved,thetwogroupsofjointtendernessnumber,jointswellingnumber,timeofmorning

6、stiffness,ESR,CRP,andotherindicators,andthechangeofthecurativeeffectoftraditionalChinesemedicineandmodernmedicinesyndrome,thecurativeeffectofcomparison.Results:Patientscansignificantlyimprovepatientsintestgroupwithsymptoms,theclinicalsymptoms,laboratory,th

7、eimprovementofTraditionalChineseMedicalsyndromewasbetterthancontrol.Conclusion:tripterygiumwilfordiimuchglucosidepiecesandbenefitingkidneyJuanbipillcertifiedsharecansignificantlyimprovepatientswithdisease,thetreatmenteffectisbetterthanmethotrexateandwillow

8、sulfonylureapyridinepieceofnitrogen.Keywordsarthritis,rheumatoid,tripterygiumwilfordiimuchglucosidepiece,benefitingkidneyJuanbipills,clinicalcurativeeffect.目录引言................................................