加味炙甘草汤治疗窦性心动过缓的临床研究

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1、提要目的：通过观察加味炙甘草汤治疗气虚血瘀型窦性心动过缓的疗效，初步探讨加味炙甘草汤治疗气虚血瘀型窦性心动过缓的作用机理。方法：将符合病例纳入标准的60例患者随机分为试验组、对照组各30例，试验组给予加味炙甘草汤治疗，对照组给予心宝丸治疗，4周为一疗程，观察疗效以及有无不良反应。结果：心动过缓疗效比较：心率、心电图疗效、24h动态心电图试验组均优于对照组，两组有显著性差异（P<0.05）；临床症状疗效：试验组在改善心悸、胸闷、神疲等方面优于对照组（P<0.05）。疾病综合疗效比较：试验组显著优于对照组（P<0.05）。结论：中药加

2、味炙甘草汤是治疗气虚血瘀型窦性心动过缓的有效方剂，对心悸、胸闷、神疲等症状有明显的改善，能够提高窦性心率，其作用机制可能与加味炙甘草汤能提高窦房结节律，改善心功能有关系。关键词加味炙甘草汤；窦性心动过缓；临床研究TheclinicalresearchofModifiedZhigancaoSouponthetreatmentofsinusbradycardiaSpeciality:InternalMedicineofTraditionalChineseMedicineAuthor:LuoChuanchaoTutor:Pro.Zhan

3、gShiliangAbstractObjective:ToobservetheclinicalcurativeeffectoftreatingsyndromeofQi-astheniaandblood-StasisofsinusbradycardiathroughapplyingtheModifiedZhigancaoSoupandToexploreitsmechanism.Methods:60patientswererandomlydividedintotheexperimentalgroup(30cases)andthecon

4、trolgroup(30cases).Xinbaopillweregiventothecontrolgroup.TheexperimentalgroupwasdosedModifiedZhigancaoSoup.Thecourseofclinicaltreatmentisfourweeks.Result:Comparedwiththecontrolgroup,experimentalgroupaftertreatmenthadremarkableeffectuponimprovingelectrocardiogram,24hour

5、sdynamicelectrocardiogram(DCG)andheartrates.Thereweresignificantdifferences(P<0.05).TheeffectonclinicalsymptomofTheexperimentalgroup,includingpalpitation,chestdistressandlassitude,wasgreatlyimproved(P<0.05).Theexperimentalgrouphadremarkableeffectuponclinicalgeneralthe

6、rapeuticeffect（P<0.05）.Conclusion:ModifiedZhigancaoSouphasgoodcurativeeffectontreatingsyndromeofQi-astheniaandblood-Stasisofsinusbradycardia,canincreaseheartrates,canappeasepalpitation,chestdistressandlassitude.ItsmechanismmaybethatModifiedZhigancaoSoupcanimprovecardi

7、acfunctionsandincreaseA-Vnodalrhythm.KeywordsModifiedZhigancaoSoup;sinusbradycardia;clinicalstudy目录引言...............................................................................................................................1临床研究...................................

8、............................................................................................2一、诊断和病例选择标准....................