大承气汤灌肠疗法对脓毒症肠功能障碍患者的临床疗效

《大承气汤灌肠疗法对脓毒症肠功能障碍患者的临床疗效》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、提要目的：观察大承气汤灌肠疗法对脓毒症肠功能障碍患者的临床疗效。方法：按照脓毒症诊断标准，采用前瞻性对照研究，选择2010年9月－2012年4月收治于山东省中医院急诊科、ICU病房的60例脓毒症患者，采用随机数字表法，随机分为两组。治疗组除西医综合治疗外，加用大承气汤灌肠，每日1次，对照组仅采用西医综合治疗。以治疗前及治疗7天后APACHEⅡ评分、白细胞计数(WBC)、C反应蛋白(CRP)为主要疗效指标。结果：大承气汤灌肠能够减轻炎症反应：治疗组治疗一周后，较对照组WBC计数有显著统计学差异(P<0.05)

2、；治疗一周后，较对照组C反应蛋白水平无显著统计学差异(P>0.05)，但治疗组治疗后C反应蛋白水平降低较对照组更明显；大承气汤灌肠能够明显改善病情严重程度，治疗结束后，治疗组APACHEⅡ评分低于治疗前，差异显著（P<0.05），对照组无明显变化。结论：大承气汤灌肠疗法能改善脓毒症肠功能障碍；减轻脓毒症患者炎症反应；减轻脓毒症肠功能障碍患者的病情严重程度。关键词脓毒症；大承气汤；灌肠疗法；肠功能障碍ClinicalefficacyofDachengqiDecoctionenematherapyonthese

3、psiswithintestinaldysfunctionSpeciality:InternalMedicineofTraditionalChineseMedicineAuthor:YaoKunTutor:Prof.WuZuoliAbstractObjective:TostudyClinicalefficacyofDachengqiDecoctionenematherapyonthesepsiswithintestinaldysfunction.Methods:Inaccordancewithsepsisd

4、iagnosisstandard,usingaretrospectivecase-controlstudy,select60SepsispatientsintheICUofAffiliatedHospitalofShandongUniversityofTCMfromSeptember2010toApril2012,usingrandomnumbertable,randomlydividedintotwogroups.ThetreatmentgroupwereofferedDachengqiDecoction

5、enematreatment(onceaday)baseduponwesternroutinetreatment,whilethecontrolgroupreceivedroutinetreatmentonly.APACHEⅡscore,WBC,CRPareselectedasthemainobservingindexesforclinicaleffects.Results:DachengqiDecoctionenematreatmentcanremarkablyimprovedseverityandpro

6、gnosisofsepsis.Comparedwithbeforetreatment,APACHEⅡscoredescendobviouslyinthetreatmentgroup(P<0.05)whiletherewasnosignificantdifferenceinthecontrolgroup.DachengqiDecoctionenematreatmentcanreducesinflammation.Intreatmentgroup,WBCcountandCRPlevelaftertreatmen

7、tarebothdecreased(P<0.05).Conclusions:DachengqiDecoctionenematreatmentccanimproveSepsiswithintestinaldysfunctionandreducetheseverityofSepsis,decreasethemortalitofpatients.KeywordsSepsis,DachengqiDecoction,Enematreatment,Intestinaldysfunction目录引言...........

8、....................................................................................................................1临床研究.......................................................................................