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ID:31989563
大小:2.47 MB
页数:39页
时间:2019-01-30
《康复新液对白色念珠菌抑菌作用和耐药基因cdr1表达的-研究》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、万方数据中文摘要水平随着药物浓度的梯度增加而降低,在浓度为1:1和更高时mRNA的表达水平受到完全抑制。结论:1本实验采用改良常量肉汤稀释法测定康复新液在体外对白色念珠菌具有一定的抗菌活性,最低杀菌浓度为(MBC)1:1,最低抑菌浓度(MIC)为1:8。2逆转录聚合酶链反应检测白色念珠菌用药后耐药基因表达减弱,说明康复新液对白色念珠菌的生物膜有一定的抑制作用。白色念珠菌相关耐药基因CDRl的表达水平随药物浓度的梯度增加而降低,在浓度为1:1及更高时mRNA的表达水平完全受到抑制。关键词:口腔念珠菌病,白色念珠菌,康复新液,最低抑菌浓度,聚合酶链反应,耐药基因万方数据英文摘要Research
2、onBacteriostasisofKangfuxinyeonCandidaalbicansandexpressionofdrug-resistanceGeneCDRlKangfuxinyeisapurenaturalmedicineofethanolextractfromthedriedperiplanetaAmericana,withrichbioactivesubstances,polyhydricalcohols,peptidesactivesubstance,including18kindsofaminoacids.Totakeitorallycancurestasisloodh
3、inders,suchasgastrorrhagia,duodenum,anabrosis,phthisis,adjuvanttherapyofdeficiencyofyin,tuberculosis,ere.Totakeitforexternalusecanclareanabrosis,trauma,bum,scald,bedsore,andothermucocutaneoushemorrhage.Atpresent,itiswidelyappliedinmanydisciplinesofclinic,andhasachievedgoodeffect.CandidaAlbicansisw
4、idelyappliedinthenature.Itiscommontoseeintheoralcavity,theupperrespiratorytract,intestinaltractandvagina.ThequantityissmallifthemorbiditydoesnotOccur.Whentheimmunityoftheorganismorimmunityisreduced,thebacteriawillbeinmasspropagation.Thediseasewillcomeifthemutualrestrictionofthenormalfloraisimbalan
5、ced.CandidaAlbicansCancausemanypartsofthehumanbodytosufferdiseases.Themucosalcandidiasis,mycoticstomatitis,angularcheilitisanddenturestomatitisarequitecommon.Inrecentyears,thenonstandardusageofthedomesticantibioticandwideclinicalapplicationofhormoneandimmunosuppressorleadtothedysbacteriosisandimmu
6、nityreducing.Besides,theratethattheskin,mucousmembranceandviscerainfectthefungusisincreased.Thedrugresistanceofthefungusbecomesstronger.Theoccurrencerateofthemouthmucousmembranecandidiasisbecomesmuchhigher.Theresearchshowsthat,amongtheinfantthrush,bacterialangularcheilitis,denturestomatitis,candid
7、aleukodermaandchronicmucousmembraneskincandida,thedetectionrateofthecandidaAlbicansiSabove50%.Atpresent,thecommolltherapeuticmethodshaveapplyingsomemedicinetotheparsortakingtheantiftmgal4万方数据英文摘要drugorally.Thesem
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