低钠血症与慢性心力衰竭患者的心脏功能和预后的关系

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时间:2019-01-29

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1、硕E学位论文英文摘要ObjectivesAbstractTheaimsofthisstudyweretOinvestigatetherelationshipsbetweenhyponatremiaandthecardiacfunctionandprognosticstatusofthepatientswithchronicheartfailure(CHF).MethodsEighthundredandsixsubjectswerecollectedfromthepatientswithCHFwhowerehospitalizedintheseco

2、ndXiangyahospitalofcentralsouthuniversityfromJuly2003tOAugust2004.ThepatientswithCHFweredividedinto2groupsaccordingtoserumsodiumlevels:normalserumsodiumgroup(Na≥135mmol/L)andlowerserumsodiumgroup(Na<135retool/L).Themethodsofcomputerizedsortingaccompanizedwithaexcerptingmedica

3、lrecordswereusedtocollecttheclinicaldata.Demographicdataandgeneralclinicaldataincludingunderlyingcardiacdiseases,concomitantdiseases,clinicalchemistry,echocardiogramresultsandresidentialtreatmentregimenswereallrecorded.ThecorrelationsofserumsodiumlevelswithNYHAcardiacfunction

4、classaswellasprognosticstatusinpatientswithCHFwereanalyzedbymulti—factorlogisticstatisticalmethod.Results1.Onehundredandtwocaseswereconcomitantwithhyponatremia,IV硕士学位论文英文摘要accountingfor12.66%ofstudypopulation.2TheproportionofhypertensionandcardiomyopathyinCHFwithhyponatremiag

5、roupwassignificantlyhigherthanthatinCHFwithnormalserumsodiumgroup(p<005),Whiletherewerenostatisticaldifferencesbetweentwogroupsingeneralinformation(includingage,gender,smoking,drinking,BMI,familyhistoryofcardiovasculardisease)andthehistoryofcoronaryheartdisease,valvulardiseas

6、eanddiabetesmellitus(P>O.05).3.Serumchlorinewasreducedsignificantlyinhyponatremiagroup(P<0.05)andthewhitebloodcellcount,thelevelsofserumureanitrogenandcreatinineincreasedsignificantlyinthehyponatremiagroup(P<0.05).Thedifferencesoflevelsoftheserumpotassium,uricacidandfastingbl

7、oodglucose(FBS),hemoglobin(Hb)andplatelet(PET)countwerenotstatisticallysignificantbetweentwogroups(P>0.05).4.UltrasonicCardiographyrevealedtheleftatrialdiameter(LAD),theleftventricularend—diastolicdiameter(LVDD)andtheleftventricularejectionfraction(LVEF)differsintwogroups(P<0

8、.05).LAD、LVDDincreasedremarkably,butLVEFdecreasedsignificantlyinthep

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《低钠血症与慢性心力衰竭患者的心脏功能和预后的关系》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库

1、硕E学位论文英文摘要ObjectivesAbstractTheaimsofthisstudyweretOinvestigatetherelationshipsbetweenhyponatremiaandthecardiacfunctionandprognosticstatusofthepatientswithchronicheartfailure(CHF).MethodsEighthundredandsixsubjectswerecollectedfromthepatientswithCHFwhowerehospitalizedintheseco

2、ndXiangyahospitalofcentralsouthuniversityfromJuly2003tOAugust2004.ThepatientswithCHFweredividedinto2groupsaccordingtoserumsodiumlevels:normalserumsodiumgroup(Na≥135mmol/L)andlowerserumsodiumgroup(Na<135retool/L).Themethodsofcomputerizedsortingaccompanizedwithaexcerptingmedica

3、lrecordswereusedtocollecttheclinicaldata.Demographicdataandgeneralclinicaldataincludingunderlyingcardiacdiseases,concomitantdiseases,clinicalchemistry,echocardiogramresultsandresidentialtreatmentregimenswereallrecorded.ThecorrelationsofserumsodiumlevelswithNYHAcardiacfunction

4、classaswellasprognosticstatusinpatientswithCHFwereanalyzedbymulti—factorlogisticstatisticalmethod.Results1.Onehundredandtwocaseswereconcomitantwithhyponatremia,IV硕士学位论文英文摘要accountingfor12.66%ofstudypopulation.2TheproportionofhypertensionandcardiomyopathyinCHFwithhyponatremiag

5、roupwassignificantlyhigherthanthatinCHFwithnormalserumsodiumgroup(p<005),Whiletherewerenostatisticaldifferencesbetweentwogroupsingeneralinformation(includingage,gender,smoking,drinking,BMI,familyhistoryofcardiovasculardisease)andthehistoryofcoronaryheartdisease,valvulardiseas

6、eanddiabetesmellitus(P>O.05).3.Serumchlorinewasreducedsignificantlyinhyponatremiagroup(P<0.05)andthewhitebloodcellcount,thelevelsofserumureanitrogenandcreatinineincreasedsignificantlyinthehyponatremiagroup(P<0.05).Thedifferencesoflevelsoftheserumpotassium,uricacidandfastingbl

7、oodglucose(FBS),hemoglobin(Hb)andplatelet(PET)countwerenotstatisticallysignificantbetweentwogroups(P>0.05).4.UltrasonicCardiographyrevealedtheleftatrialdiameter(LAD),theleftventricularend—diastolicdiameter(LVDD)andtheleftventricularejectionfraction(LVEF)differsintwogroups(P<0

8、.05).LAD、LVDDincreasedremarkably,butLVEFdecreasedsignificantlyinthep

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