低钠血症与慢性心力衰竭患者的心脏功能和预后的关系

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1、硕E学位论文英文摘要ObjectivesAbstractTheaimsofthisstudyweretOinvestigatetherelationshipsbetweenhyponatremiaandthecardiacfunctionandprognosticstatusofthepatientswithchronicheartfailure(CHF)．MethodsEighthundredandsixsubjectswerecollectedfromthepatientswithCHFwhowerehospitalizedintheseco

2、ndXiangyahospitalofcentralsouthuniversityfromJuly2003tOAugust2004．ThepatientswithCHFweredividedinto2groupsaccordingtoserumsodiumlevels：normalserumsodiumgroup(Na≥135mmol／L)andlowerserumsodiumgroup(Na<135retool／L)．Themethodsofcomputerizedsortingaccompanizedwithaexcerptingmedica

3、lrecordswereusedtocollecttheclinicaldata．Demographicdataandgeneralclinicaldataincludingunderlyingcardiacdiseases，concomitantdiseases，clinicalchemistry,echocardiogramresultsandresidentialtreatmentregimenswereallrecorded．ThecorrelationsofserumsodiumlevelswithNYHAcardiacfunction

4、classaswellasprognosticstatusinpatientswithCHFwereanalyzedbymulti—factorlogisticstatisticalmethod．Results1．Onehundredandtwocaseswereconcomitantwithhyponatremia，IV硕士学位论文英文摘要accountingfor12．66％ofstudypopulation．2TheproportionofhypertensionandcardiomyopathyinCHFwithhyponatremiag

5、roupwassignificantlyhigherthanthatinCHFwithnormalserumsodiumgroup(p<005)，Whiletherewerenostatisticaldifferencesbetweentwogroupsingeneralinformation(includingage，gender，smoking，drinking，BMI，familyhistoryofcardiovasculardisease)andthehistoryofcoronaryheartdisease，valvulardiseas

6、eanddiabetesmellitus(P>O．05)．3．Serumchlorinewasreducedsignificantlyinhyponatremiagroup(P<0．05)andthewhitebloodcellcount，thelevelsofserumureanitrogenandcreatinineincreasedsignificantlyinthehyponatremiagroup(P<0．05)．Thedifferencesoflevelsoftheserumpotassium，uricacidandfastingbl

7、oodglucose(FBS)，hemoglobin(Hb)andplatelet(PET)countwerenotstatisticallysignificantbetweentwogroups(P>0．05)．4．UltrasonicCardiographyrevealedtheleftatrialdiameter(LAD)，theleftventricularend—diastolicdiameter(LVDD)andtheleftventricularejectionfraction(LVEF)differsintwogroups(P<0

8、．05)．LAD、LVDDincreasedremarkably,butLVEFdecreasedsignificantlyinthep