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ID:31948834
大小:4.18 MB
页数:47页
时间:2019-01-29
《阿伐他汀单用与与辅酶q10联用对急性脑卒中血脂和肝功能的影响》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、万方数据泰山医学院硕士毕业论文疗后,血液中AST水平在2周后有明显升高,但是在随后的时间内,趋于稳定,可见辅酶QlO对于患者服用阿伐他汀药物引起的
2、衄液AST的升高具有明显的保护作用。通过对患者的肝酶AST检查发现:单独使用阿伐他汀组的患者经过2周、1月的治疗后,AST水平较治疗前均有显著的差异(p<0.05),并且治疗2周与治疗1月患者AST检查发现:两者的AST水平具有显著性差异(p<0.05),说明译独使用阿伐他汀有明显的升高肝酶ALT的作用。阿伐他汀联合辅酶QlO组患者在治疗前与治疗后2周、1月的AST检查
3、未出现显著的差异(p>0.05),说明阿伐他汀联合辅酶Q10不会对患者AST水平造成影响。(8)经过对患者网一治疗时间内两组闭AsT及ALT比较发现,在经过两种治疗方法后的患者,AST、ALT水平在2周、1月都有明显的差异。t'3E(p4、4万方数据泰山医学院硕士毕业论文AToRVASTATINMONoTHERAPYANDTHEEFFECToNBLOoDLIPIDANDLIVERFUNCTIONOFACUTECEREBRALAPoPLEXYCOMBINEDWITHCOENZYMEQ10A_BSTRACTTutors:Prof.ShangZhanpingPostgraduate:CaiLiminProfessional:pathologyandpathophysiologyObjcct:Bycomparingtheseparateuseofatorva5、statinandatorvastatinandcomparetheeffectofcoenzymeQ10attxiliaryroutinedoseoftwogroupsofpatientswithliverfunction,todeterminethepreventiveeffectofcoenzyineQIOonatorvastatindrugrelatedhepaticinjury,SOastotheclinicalrationaluseofdrugs,toprovidethetheoreticalbase。6、Methods:SelectingPingyinCountyPeople’SHospitalin2012Decemberto2013OctoberinDepartmentofinternalmedicinewerediagnosedasischemicstrokepatients,consistentwiththe2010,neuropathy,cerebrovasculardiseasegroupissuedguidelinesfordiagnosisandtreatmentofacuteischemicstro7、keChina【1】ChineseMedicalAssociation,atotalof77cases,mcludmg42casesofmale,35casesfemale.111epatientswererandomlydividedinto2groups,onegroupisusedaloneatorvastatingroup,basedonroutinetreatmentforstroke,oralatorvastatin20mg/late;secondgroupsofatorvastatinandcoenz8、ymeQ10group,whichisbasedon20mg/oflateinoralah,supportingtheuseofcoenzymeQ10,everytime20mg,threetimesaday,combinedtreatmentgroup.Allthepatientsweredeterminedbeforetreatmentinliverfunctionafteradmission,andintheuseofdrugsfor2weeksandafterJanuary,respectively.the9、liverfunction.11ledynamicchangesofliverfunctioninpatientswimrecords,iftransaminaseelevationasnormalreferencevaluesofmorethanthreetimes,stoptakingthemedication.Exclusioncriteria:lpa
4、4万方数据泰山医学院硕士毕业论文AToRVASTATINMONoTHERAPYANDTHEEFFECToNBLOoDLIPIDANDLIVERFUNCTIONOFACUTECEREBRALAPoPLEXYCOMBINEDWITHCOENZYMEQ10A_BSTRACTTutors:Prof.ShangZhanpingPostgraduate:CaiLiminProfessional:pathologyandpathophysiologyObjcct:Bycomparingtheseparateuseofatorva
5、statinandatorvastatinandcomparetheeffectofcoenzymeQ10attxiliaryroutinedoseoftwogroupsofpatientswithliverfunction,todeterminethepreventiveeffectofcoenzyineQIOonatorvastatindrugrelatedhepaticinjury,SOastotheclinicalrationaluseofdrugs,toprovidethetheoreticalbase。
6、Methods:SelectingPingyinCountyPeople’SHospitalin2012Decemberto2013OctoberinDepartmentofinternalmedicinewerediagnosedasischemicstrokepatients,consistentwiththe2010,neuropathy,cerebrovasculardiseasegroupissuedguidelinesfordiagnosisandtreatmentofacuteischemicstro
7、keChina【1】ChineseMedicalAssociation,atotalof77cases,mcludmg42casesofmale,35casesfemale.111epatientswererandomlydividedinto2groups,onegroupisusedaloneatorvastatingroup,basedonroutinetreatmentforstroke,oralatorvastatin20mg/late;secondgroupsofatorvastatinandcoenz
8、ymeQ10group,whichisbasedon20mg/oflateinoralah,supportingtheuseofcoenzymeQ10,everytime20mg,threetimesaday,combinedtreatmentgroup.Allthepatientsweredeterminedbeforetreatmentinliverfunctionafteradmission,andintheuseofdrugsfor2weeksandafterJanuary,respectively.the
9、liverfunction.11ledynamicchangesofliverfunctioninpatientswimrecords,iftransaminaseelevationasnormalreferencevaluesofmorethanthreetimes,stoptakingthemedication.Exclusioncriteria:lpa
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