john snow and the broad street cholera outbreak of 1854

john snow and the broad street cholera outbreak of 1854

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时间:2018-12-07

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1、JohnSnowandtheBroadStreetCholeraOutbreakof1854CholerareachedtheBritishIslesintheearly1830s,andoutbreakswouldcontinueforthenextfiftyyears.Today,itiswellknownthatcholeraiscausedbythebacteriaVibriacholeraeandisusuallyspreadinpoordrinkingwater.Earlytheoriesblamedtheinfec

2、tiononmistsand'miasmas',whichledtomanyoftheearlyattemptstocontrolcholerafailing.Inrealitythepoorsanitaryconditionsofacity'swatersupplywasresponsible.EarlyVictoriancitiesalsoincludedcowshedsmixedinamongstthehouses.Thesecombinedwithpoorhandlingofhumansewage(oftenmerely

3、aholeintheground)ledtoarapidcontaminationofthedrinkingwater.Indeed,thefamousBroadStreetwaterpump(seebelow)wasashallowwaterpumpthatpumpedwaterfromthecontaminatedwatertable.Inthe1850s,JohnSnowperformedpioneeringdataanalysistoprovehishypothesisthatcholerawasspreadinthed

4、rinkingwater.Thisanalysisifperformedtoday,wouldcomeundertherealmsofGIS(GeographicInformationSystems)andDataMining.SomehaveclaimedhisBroadStreetmapasbeingthefirstexampleofGIS,eventhoughitwasperformedwithapenandpaper.Althoughthisisanexaggeration,theBroadStreetmapitisan

5、excellentexampleofthepowerofmapstoclearlydemonstraterelationshipsincomplexscenarios.Snow'sworkwiththeLondoncholeraoutbreaksofthe1850s,isoftencitedasthebeginningofmodernepidemiology.Unfortunatelywordofthispioneeringepidemiologywasslowtospread,andtheLondoncholeraoutbre

6、akswouldcontinueintothe1880swhenalloftheshallowwater-pumpswerefinallydecommissioned.ThispagelooksatSnow'stwomostfamousanalysiscasesthathelpedtoprovehishypothesisthatcholerainfectionsoccurredthroughdrinkingwater.TheBroadStreetOutbreak,1854Thisisthemostfamouspieceofdat

7、aanalysisperformedbyJohnSnow,andhispromptactionundoubtedlysavedmanylives.TheoutbreakoccurredintheSohoDistrictofLondon,inandaroundBroadStreet.JohnSnowreasonedthatifcholerawasspreadbyamistormiasma,astheprevailingtheoriessuggested,thenthecasesshouldbeuniformlydistribute

8、dalongthestreets.Toseeifthiswasthecase,heplottedeachcholeracaseonamap,similartotheoneontheleft.Healsoplottedhouseswithmultiplecases

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