脑干听觉诱发电位和脑血流动力学对脑瘫的临床评估探讨

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1、脑干听觉诱发电位和脑血流动力学对脑瘫的临床评估探讨【摘要】目的探讨脑干听觉诱发电位和脑血流动力学变化对脑瘫（CP）的临床评估价值。方法收集脑瘫患儿70例，分为轻型组、中型组、重型组三组。采用脑干听觉诱发电位检测I波、III波、V波的潜伏期，I〜III波、IV〜V波、I〜V波的波峰间潜伏期，并采用经颅多普勒超声技术检测脑内动脉平均血流速度（Vm）.动脉搏动指数（PI）、血管阻力指数（RI）的变化。结果脑瘫患儿重型组和中型组的脑干听觉诱发电位异常表现以潜伏期或波峰间潜伏期延长明显，分别为13例（18.6%）和16例（22.9%）,与轻型组比较，差异有统计学意义（

2、P<0.05）；同时，中型组和重型组Vm均降低，与轻型组比较，差异冇统计学意义（P〈0.05或0.01）；中型组和重型组PI、RI均升高，与轻型组比较，差异有统计学意义（P〈0.05或0.01）o结论脑干听觉诱发电位联合脑血流动力学检测对CP的早期诊断、病情判断和预后等可提供有价值的参考。【关键词】脑干听觉诱发电位；脑血流动力学；脑瘫中图分类号：R748文献标识码：ADOI:10.3969/j.issn.10031383.2015.05.002Clinicalcvaluationofbrainstemauditoryevokedpotentialandcer

3、ebralhemodynamicsforcerebralpalsy[HJ2][HJ]HUANGYueyan,LIQingfeng,PANHongfei,LIQiang,TANGHanqing,HUANGYunfeng,YOUJinyong,HUANGKen(AffiliatedHospitalofYoujiangMedicalUniversityforNationalities,Baise533000,Guangxi,China)[HJ2][HJ][Abstract】ObjectiveToexploreclinicalevaluationofbrainste

4、mauditoryevokedpotentials(BAEP)andcerebralhemodynamicsforcerebralpalsy(CP)・Methods70childrenwithCPwerecollectedanddividedintomilddegreegroup,middledegreegroupandseveredegreegroup.AndthenBAEPwasusedtodetectpeaklatency(PL)ofwaveI,waveIIIandwaveVaswellasinterpeaklatency(IPL)ofwaveI~II

5、I,waveIV~VandwaveI〜V.Inaddition,meanflowvelocityofcerebralartery(Vm),arterialpulsationindex(PI)andvascularresistanceindex(RI)weredetectedthroughtranscranialDoppler(TCD)・ResuItsAbnonnalBAEPwasfoundin13cases(18.6%)inseveredegreegroupand16cases(22.9%)inmiddledegreegroup,whichshowedtha

6、ttheyobviouslyproIongatedinPLandIPL,anddiffereneewasstatisticallysignificantwhencomparingtothoseinmilddegreegroup(P<0.05).Inaddition,Vmofmiddledegreegroupandseveredegreegroupdecreased,andtherewasstatisticallysignificantor0.01)•However,PIandRIinbothseveredegreegroupandmiddledegreegr

7、oupincreased,differencewasstatisticallysignificantwhencomparingtothoseinmilddegreegroup(P<0.05or0.01)•ConclusionBAEPcombinedwithcerebralhemodynamicscanprovidevaluablereferenceforearlydiagnosis,conditionjudgmcntandprognosisofCP.[Keywords]BAEP；cerebralhemodynamics；CP缺血缺氧造成的脑损伤常常是小儿脑性

8、瘫痪(cerebralpalsy,CP)、新生儿缺氧