术中应用血管活性药物对非停跳冠脉搭桥术患者术后神经系统的影响

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1、授予单位代码10089学号或申请号20153091中国图书分类号R971+.93HebeiMedicalUniversity硕士学位论文专业学位术中应用血管活性药物对非停跳冠脉搭桥术患者术后神经系统的影响研究生：刘岩导师：韩建民教授专业：麻醉学二级学院：河北医科大学第二医院2018年3月目录中文摘要···································································································1

2、英文摘要···································································································3英文缩写···································································································5研究论文术中应用血管活性药物对非停跳冠脉搭桥术患者术后神经系统的影响前言······

3、·····························································································7材料与方法····················································································7结果································································

4、··········································11附图··········································································································13附表······························································································

5、···········14讨论··········································································································19结论··········································································································21参考文献·············

6、·····················································································22综述非停跳冠脉搭桥术术后谵妄研究进展··············································26致谢·······························································································

7、····38个人简历···································································································39中文摘要术中应用血管活性药物对非停跳冠脉搭桥术患者术后神经系统的影响摘要目的：通过对非停跳冠脉搭桥术(Off-pumpcoronaryarterybypassgrafting，OPCABG)患者围术期随访，探讨术中应用去甲肾上腺素和麻黄碱对其术后神经系统的影响。方法：选择行OP

8、CABG患者100例。根据术中是否应用血管活性药物分为用药组（D组）及未用组（N组）。D组根据使用药物种类分为去甲肾上腺素组（D1组）、麻黄碱组（D2组）、合用组（D3组）。依照单次去甲肾上腺素使用剂量分为≥10μg组（NE1组）及＜10μg组（NE2组）。记录术后神经系统并发症情况，得出结论。结果：1.100例患者中，38例（38.0%）出现术后神经系统并发症。2.100例患者中，38例（38.0%）术中使用血管活性药物。3.D组和N组高血压患病率为71.1%和45.2%，术后神经系统并发症发