文多灵在大鼠体内外代谢及对细胞色素p450酶活性影响的研究

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1、授予单位代码10089学号或申请号20152351中国图书分类号R917HebeiMedicalUniversity硕士学位论文学术学位文多灵在大鼠体内外代谢及对细胞色素P450酶活性影响的研究研究生:张玉倩导师：王巧教授专业：药物分析学二级学院：药学院2018年3月目录中文摘要················································································1英文摘要·························································

2、························5英文缩写···············································································10研究论文文多灵在大鼠体内外代谢及对细胞色素P450酶活性影响的研究引言···············································································11第一部分文多灵在大鼠肝微粒体CYP450酶中的代谢产物及代谢亚型酶的研究前言··················

3、·····························································13材料与方法······································································14结果···············································································18附图·························································

4、······················22附表···············································································27讨论···············································································29小结···············································································30参考文献·····

5、····································································30第二部分文多灵在大鼠体内代谢的研究前言···············································································32材料与方法······································································33结果·································

6、··············································36附图···············································································42附表···············································································47讨论··································································

7、·············50小结···············································································51参考文献·········································································51第三部分文多灵对大鼠CYP450不同亚型酶体外代谢活性的影响前言·········································································

8、······52材料与方法·············