右美托咪定对脓毒症或脓毒性休克患者预后影响的meta分析

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1、授予单位代码10089学号或申请号20153327中图分类号R459.7HebeiMedicalUniversity硕士学位论文专业学位右美托咪定对脓毒症或脓毒性休克患者预后影响的Meta分析研究生：秦锤雷导师：董士民教授专业：急诊医学二级学院：河北医科大学第三医院2018年3月目录中文摘要········································································································1英文摘要····················

2、····················································································2英文缩写········································································································4研究论文右美托咪定对脓毒症或脓毒性休克患者预后影响的Meta分析前言···············································

3、·························································5材料与方法····························································································6结果········································································································8附图··········

4、······························································································10附表········································································································13讨论·····································································

5、···································14结论········································································································16参考文献································································································16综述右美托咪定在脓毒症治疗中的研究及其进展·······

6、·························20致谢················································································································27个人简历········································································································28中文摘要右美托咪定对脓毒症或脓毒性休克患者预

7、后影响的Meta分析摘要目的：应用meta分析的方法研究右美托咪定对脓毒症或脓毒性休克患者预后的影响。方法：计算机检索相关电子数据库，包括Pubmed数据库、Cochrane临床试验数据库、EMBASE数据库、WebofScience数据库、万方数据库、中国知网及中国生物医学文献数据库从建库起至2018年01月的有关文献。制定研究纳入和排除标准，对符合纳入标准的研究进行质量评价并进行数据提取。采用RevMan5.3软件对短期病死率〔重症监护病房（ICU）病死率或28天病死率〕、ICU住院时间、机械通气时间进行meta分析。病死率采用相对危险度（

8、RR）及95%可信区间（CI）表示，ICU住院时间、机械通气时间用标准化均数差（SMD）及95%可信区间（CI）表示。结果：根据文献检索策略制定的标准