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1、右美托咪陡复合舒芬太尼在骨科术后自控静脉镇痛中的应用分析沈阳市军区总医院麻醉科辽宁沈阳110840【摘要】目的:探讨右美托咪啶复合舒芬太尼在骨科自控静脉镇痛屮的临床疗效。方法:将180例行骨科手术治疗的患者,随机分为三组,分别应用曲马多复合舒芬太尼(A组)、右美托咪啶复合舒芬太尼(B组)和舒芬太尼(C组),观察三组患者进行术后自控静脉镇痛效果,比较T1-T5时间点血流动力学影响、疼痛视觉模拟评分(VAS),Ramsay镇静评分、镇痛泵追加次数评估以及不良反应。结果:与B组相比,组间比较差异显著(P<0.01)。与A组相
2、比,B、C组VAS评分显著低于A组,差异显著(P<0.01)。B组在T2-T4时间点上的Ramsay镇静评分优于A、C组,镇静镇痛效果比较,差异有统计学意义(P<0.01)。B组按压次数明显少于A组及C组,差异有统计学意义(P<0.01>。结论:右美托咪啶复合舒芬太尼用于骨科手术后静脉镇痛的临床疗效显著,不良反应少,安全可靠,值得应用推广。【关键词】右美托咪啶;舒芬太尼;血液动力学;自控静脉镇痛【屮图分类号】R614【文献标识码】B【文章编号】1764-8999(2015)7-0703-02Clinical
3、ApplicationofDexmedetomidineHydrochlorideInjectioncombinedwithSufentanilIntravenousInjectioninPalient-controlledIntravenousAnalgesiaPostoperalionforOrthopedicsOperationZouJi-He,JinChun-Ji,Zhoujin*Departmentofanesthesiology,GeneralHospitalofShenyangCommand,LiaoningS
4、henyang,110016,China【Abstract】Objective:Analysisofrightdexmedetomidinecombinedwithsufentanilinorthopedicscontrolledintravenousanalgesiainclinicalefficacy.Methods:180casesinorthopedicsurgerypatientswhowererandomlydividedintothreegroups,tramadolcombinedwithsufentanil
5、(Agroup),rightdexmedetomidinecombinedwithsufentanil(groupB),Shufentanyl(groupc),observepatient-controlledintravenousanalgesiathreegroupsofeffects,comparethehemodynamiceffectsofpainvisualanalogscale(VAS),Ramsaysedationscore,thenumberofadditionalanalgesiaassessmentad
6、versereactions.Results:comparedwithgroupA,B,GroupCscoresweresignificantlylowerthaningroupA,thedifferencewassignificant(P<0.01)•GroupBonT2-T4timepointRamsaysedationscorebetterthanA,GroupC,sedativeandanalgesiceffects,thedifferencewasstatisticallysignificant(P<0
7、.01).Conclusion:TheclinicaleffectofDexmedetomidineHydrochlorideInjectioncombinedwithSufentanilIntravenousInjectioninPalient-controlledIntravenousAnalgesiaPostoperalionforOrthopedicsOperationissignificant,adversereactions,safeandreliable,worthyapplicationpromotion.【
8、Keywords】DexmedetomidineHydrochlorideInjection;SufentanilIntravenousInjection;Hemodynamic;PCIA病人自控静脉镇痛技术目前已在临床广泛应用,特别是针对术后急性疼痛的治疗,但是由于手术类型不同及存在个体