资源描述:
《阴道镜指引下多点活检在宫颈上皮内瘤样病变诊断中的作用》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、阴道镜指引下多点活检在宫颈上皮内瘤样病变诊断中的作用【摘要】目的:比较阴道镜指引下多点活检与宫颈锥切术后病理结果的差异,评价阴道镜指引下宫颈活检在高级别宫颈上皮内瘤变(CINII,III)诊断中的作用。方法:645例阴道镜指引下多点活检病理为CINII及以上级别病变(CINII+)的患者行子宫颈锥切术,对比锥切术前后的病理结果。结果:阴道镜指引下多点活检诊断CINII+敏感度95.0%,特异度46.2%,子宫颈锥切术前后CINII,III病理的一致性72.86%,漏诊宫颈浸润癌2.22%。结论:阴道镜指引下子宫颈多点活检是诊断CINII,III的一种
2、简单而有效的方法,与子宫颈锥切术后的病理一致性为72.86%,进一步处理的选择应综合评估。【关键词】子宫颈锥切术;阴道镜指引下活检;宫颈上皮内瘤变。Effectofcolposcopy-directedcervicalbiopsyinthediagnosisofcervicalintraepithelialneoplasmLIUYanl,CHENRuil,BIHui2.1.DepartmentofGynecology,TheSecondHosipitalofBeijing,Beijing100031,China;2.DepartmentofGynec
3、ology,PekingUniversityFirstHospital,Beijing100034,China阴道镜指引下多点活检在宫颈上皮内瘤样病变诊断中的作用【摘要】目的:比较阴道镜指引下多点活检与宫颈锥切术后病理结果的差异,评价阴道镜指引下宫颈活检在高级别宫颈上皮内瘤变(CINII,III)诊断中的作用。方法:645例阴道镜指引下多点活检病理为CINII及以上级别病变(CINII+)的患者行子宫颈锥切术,对比锥切术前后的病理结果。结果:阴道镜指引下多点活检诊断CINII+敏感度95.0%,特异度46.2%,子宫颈锥切术前后CINII,III病理
4、的一致性72.86%,漏诊宫颈浸润癌2.22%。结论:阴道镜指引下子宫颈多点活检是诊断CINII,III的一种简单而有效的方法,与子宫颈锥切术后的病理一致性为72.86%,进一步处理的选择应综合评估。【关键词】子宫颈锥切术;阴道镜指引下活检;宫颈上皮内瘤变。Effectofcolposcopy-directedcervicalbiopsyinthediagnosisofcervicalintraepithelialneoplasmLIUYanl,CHENRuil,BIHui2.1.DepartmentofGynecology,TheSecondHos
5、ipitalofBeijing,Beijing100031,China;2.DepartmentofGynecology,PekingUniversityFirstHospital,Beijing100034,China[Abstract]Objectives:Tocomparethepathologyresultdifferencebetweentrachelectomyandcolposcopy-directedcervicalbiopsytoevaluatethediagnosticeffectivenessofcolposcopy-direc
6、tedpunchbiopsiesforthepatientswithhigh-levelcervicallesions(CINIIandCINIII).Methods:645patientswithCINIIandCINIIIdiagnosedbypathologyofpunchbiopsyundercolposcopywerefollowedbytrachelectomy.Thecomparisonofhistologicalpathologywasmadebetweenthetwoprocedures.Results:Thesensitivity
7、ofcolposcopy-directedpunchbiopsieswas95%,whilethespecificitywas46.2%.Theconsistenceratebetweenpunchbiopsyandexcisionalprocedureswas72.86%(459/630).2.22%ofthepunchbiopsywasupgradedtobeinvasivecarcinomabyexcisionalprocedures.Conclusions:Colposcopy-directedpunchbiopsyisasimpleande
8、ffectivemethodfordiagnosingCINIIandCINIII,whichhasacon