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1、急性心肌梗死患者住院治疗的药物分析冯碧容(四川省南充卫生学校附属医院内科四川南充637000)【摘要】目的：探讨急性心肌梗死患者住院药物治疗。方法：木次选取急性心肌梗死患者100例，均为我院心血管内科2014年3月至2015年4月收治，随机分组，就阿司匹林单用治疗(对照组，n=50)与联用氯毗格雷治疗(观察组，n=50)效果展开对比，回顾临床资料。结果：观察组选取的急性心肌梗死病例梗死后心绞痛率为2%,无再发心肌梗死及死亡事件，对照组分别为10%,6%,8%,有统计学差异(P<0.05)o观察组血管再通率为46%,对照组为44%,无明
2、显差异(P>0.05)。观察组再闭塞率为4%,对照组为16%,有统计学差异(P<0.05)。两组治疗前LVEF无明显差异，治疗后观察组明显升高，对照组不明显，组间有统计学差异(P<0.05)◊两组凝血指标疗前无差异，疗后APTT均升高(P<0.05),但组间无差异(P>0.05),两组PT、Pit治疗后与疗前均无差异(P>0.05)o结论：氯毗格雷与阿司匹林联合治疗急性心肌梗死，未增加出血风险，可使住院期间患者心血管事件率降低，最大程度保障预后，对提高临床效果意义显著。【关键词】急性心肌梗死；阿司匹林：氯
3、毗格雷【中图分类号】R45【文献标识码】A【文章编号】1007-8231(2015)08-0019-02【Abstract】ObjectiveTostudythedrugtreatmentinpatientswithacutemyocardialinfarction(mi)wasinthehospital.MethodsTheselected100casesofpatientswithacutemyocardialinfarction(mi),allareourcardiovascularinternalmedicineinMarch201
4、4toApril2015,arandomized,asaspirintherapyalone(thecontrolgroup,n=50)andcombinationwithclopidogreltherapy(observationgroup,n=50)contrasteffect,reviewofclinicaldata.ResultsObservationgroupselectedcasesofacutemyocardialinfarctionanginapectorisafterinfarctionratewas2%,norecurr
5、enceofmyocardialinfarctionanddeath,thecontrolgroupwere10%,6%,8%,statisticallysignificant(P<0.05).Bloodvesselstothe46%rateofobservationgroupandcontrolgroupwas44%,nosignificantdifference(P>0.05).Observationgroupandocclusionratewas4%,controlgroupwas16%,statisticallysign
6、ificant(P<0.05).NoobviousdifferencewasfoundbetweenthetwogroupsbeforetreatmentLVEF,increasedsignificantlyaftertreatmentgroup,controlgroupisnotobvious,thedifferencebetweengroups(P<0.05).Coagulationindexbeforetreatmentdifferencesbetweenthetwogroups,APTTwereincreasedafte
7、rtreatment(P<0.05),butnodifferencebetweengroups(P>0.05),twogroupsofPT,Pitandhealingaftertreatmenthadnodifference(P>0.05).ConclusionsClopidogrelandaspirincombinationtherapyofacutemyocardialinfarction(mi),didnotincreasetheriskofbleeding,mayleadtocardiovascularevents
8、inpatientswithhospitalizationrateisreduced,thegreatestdegreeensuretheprognosis,toimprovet
