药物涂层球囊治疗股腘动脉硬化闭塞的疗效与安全性评价

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1、授予单位代码10089学号或申请号10010010057中国图书分类号R543.5硕士学位论文专业学位药物涂层球囊治疗股腘动脉硬化闭塞的疗效与安全性评价研究生：马凯导师：毕伟教授专业：外科学二级学院：河北医科大学第二医院2018年3月目录中文摘要············································································································1英文摘要······················································

2、······················································2英文缩写············································································································4研究论文药物涂层球囊治疗股腘动脉硬化闭塞的疗效与安全性评价前言···························································································

3、·················5材料与方法································································································6结果··········································································································9附图···························································

4、···············································11附表··········································································································13讨论··········································································································16结论···················

5、·······················································································20参考文献··································································································20综述下肢动脉硬化闭塞腔内治疗的研究进展···································25致谢·······································

6、···········································································33个人简历··········································································································34中文摘要药物涂层球囊治疗股腘动脉硬化闭塞的疗效与安全性评价摘要目的：对比药物涂层球囊与普通球囊在股腘动脉硬化闭塞治疗中的疗效与安全性。方法：收集明确诊断股腘动脉硬化闭塞的患者42例，其中包括原发狭窄性病

7、变28例,闭塞性病变14例。随机分为实验组（药物涂层球囊）21例和对照组（普通球囊）21例。记录两组患者手术前及手术后6个月的观察晚期管腔丢失(LLL)、最小管腔直径(MLD)、踝肱指数(ABI)、Rutherford分级、再狭窄率、以及临床不良事件发生情况。结果：手术前MLD、ABI、Rutherford分级，术后一周Rutherford分级及术后即刻的MLD，两组均无统计学差异(P>0.05)；术后6个月实验组MLD明显高于对照组(P<0.05)，而LLL明显低于对照组(P<0.05)；术后1周及术后6个月AB