镜像动脉瘤发生、影像学及治疗

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1、Genesis,ImagingandTreatmentofIntracranialMirrorAneurysms(MirANs)InstituteofDiagnosticandInterventionalRadiology,TheSixthAffiliatedPeople’sHospital,ShanghaiJiaoTongUniversityTANHUA-QIAOMD.Ph.D.DefinitionofMirANUncommon，specialsubgroupofmutipleintracranialaneurysms;occuringatroughlythesameloc

2、ationoneachsideinthesamepatientwithoutconsideringthesizeoftheaneurysms.↙↘→←HypothesisongenesisandgrowthofMirANsAdifferentetiologicprocessoccursinmirroraneurysmdisease.Acongenitalpredisposition,andtheearlyembryologicalderangementofvascularwallformationmightbeoneoftheirunderlyingcauses.Earlyr

3、uptureinpatientswithnoextrinsicriskfactorssupporttheroleofacongenitalpredispositionoverdegenerativecausesinthepatientswithMirAN.Hemodynamicforcesmightberesponsiblefortriggeringthedevelopmentofananeurysmintheprimarilyabnormalvesselwall.EpidemiologyofMirANsPrevalence:Constitutelessthan5%ofove

4、rallaneurysmsAccountforapproximately20%–30%amongmultipleaneurysmsFamilialandtwinintracranialaneurysm:65～70%Non-familial,sporadicintracranialaneurysm:～21%Ourresultfrom190patientsharboringmutipleintracranialaneurysmsbetweenJune2007andJuly2011MANsaccountfor26.3%amongmultipleaneurysmsEpidemiolo

5、gyofMirANLocationCommonlocation:MCAbifurcationandPCoAreportedbyliteratureUncommonsite:ACAA1,Pericallosal,VertebralArteryOurresultfrom50patientswithMirANbetweenJune2007andJuly2011MCAbifurcation(10%)PCoA/C7(24%)C6(24%)C5(20%)C4(20%)Otherlocation(2%)EpidemiologyofMirANsGenderdistributionMirANV

6、SnMirANswithmutipleintracranialaneurysms-Female/maleratio:3.1:1VS2.1:1Female/maleratioofMirANsandnMirANsincreasedwiththeage<40-yearsMirANsVSnMirANs:1.5:1VS1:1>60-yearsMirANsVSnMirANs:7:1VS9:1Ourresultfrom50patientswithMirANbetweenJune2007andJuly2011Female/maleratio:2.3:1EpidemiologyofMirANs

7、Averageageatpresentation/ruptureforMirANsandnMirANspatientswasinthe5thdecadeWomenpresentedlaterthanmeninMirANsandnMirANsOurresultfrom50patientswithMirANsMeanageofMirANspresentation：62.4±12.5yearsWomenvsMenforMirANs：62.1±12.3vs63±13.4(P>0.05)SAHoccurredin