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1、WholebrainCTperfusiondeficitsusing320-detector-rowCTscannerinTIApatientsareassociatedwithABCD2scoreInternationalJournalofNeuroscience,2014;124(1):56–60Introduction01Methods02Results03Discussion04Conclusion05Atransientischemicattack(TIA)isconsideredacerebralischemiceventwithoutendorgandamag
2、eorlossofbraintissue.DespitenewerguidelinesdifferentiatingTIAfromstroke,thereremainscontroversybetweena“time-based”and“tissue-based”definitionofTIA.IntroductionResponsiblebloodvesselsforinternalcarotidarterysystemofTIApatientsmainlyforhemiplegia,aphasiaandpartialbodyfeelsobstacleandsoon.Re
3、sponsibilityforvertebralarteryvesselssystemmainlydisplaysinthepatientswithTIAvertigo,doublevision,difficultyswallowing,etcBecauseMRIdiffusionweightedimaginginformationinfersatleast“potentialinfarction,”wheretissuecannolongerbesaved,ratherthanischemia,perfusionimagingeitherviaMRIorCTisusedt
4、odeterminetissueatriskbutnotyetinfracted,alsoknownaspenumbra.Perfusionmodalitiesgiveabetterrepresentationofpenumbraortissueatriskbuthavenotinfarcted.01ArecentstudyhasdemonstratedthatasignificantportionTIApatientshaveperfusionchangesusing64detectorrowpartialbrainperfusionstudies.Additionall
5、y,wholebrainperfusion,usinghigherdetectorrowCTscanners,hasnotbeennotedintheliteraturewhichcouldbemoresensitiveindeterminingtheproportionofTIApatientsthathaveperfusionabnormalities.02Currently,theABCD2scoreisusedasapredictivetooltodetermineTIApatientswhoareathighestriskofstrokepost-TIA.Asth
6、eABCD2scoredeterminesimmediateand3-monthstrokeriskafterTIAbasedonpresentingsymptoms,itprovidesanadditionalmarkerofpotentialstrokerisk.CTperfusionOutpositiveweeksofintravenousinjectionofiodinecontrastCTmachineisusedforcontinuousscanningoftissueororganofinterestarea,measuredtimedensitycurveb
7、yareasofinterest,interestedincomputingareaofperfusionparameters,suchascerebralbloodflow,cerebralbloodvolume,averageandtmax,overtime,andcanbeappliedatthesametimethepseudocolormaplikevisualdisplay,usingperfusionimagingtostudythecharacteristicsoftissueperfusionby
