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ID:15133376
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时间:2018-08-01
《体外循环和非体外循环冠状动脉旁路移植术麻醉方法及术后恢复的对比研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、体外循环和非体外循环冠状动脉旁路移植术麻醉方法及术后恢复的对比研究作者:周琪,王刚,高长青,陈婷婷,李佳春【摘要】目的比较体外循环和非体外循环冠状动脉旁路移植术(OPCAB)的麻醉方法及术后恢复情况。方法131例择期行冠状动脉旁路移植术(CABG)患者随机分为体外循环组(on-pump组,n=45)和非体外循环组(off-pump组,n=86),比较两组的麻醉药用量,术中失血及补液,麻醉恢复,术后并发症以及心肌酶变化等情况。结果两组患者术前资料相似。off-pump组麻醉时间较on-pump组短[(244±47)minVs(312±59)min](P<0.05)。on-pump组术中出血
2、量、自体血回输量、红细胞、血浆及血小板用量均多于off-pump组(P<0.05)。两组患者血管吻合支数[off-pump组(2.7±0.6)Vson-pump组(2.9±0.7)]无显著差异(P>0.05)。两组患者围术期均无死亡。与on-pump组相比,off-pump组术后苏醒时间、呼吸机辅助时间、气管导管拔出时间及ICU停留时间明显缩短(P<0.05)。off-pump组术后肾、肺及中枢神经系统并发症发生率明显低于on-pump组(P<0.05)。两组CK-MB术后均升高,on-pump组明显高于off-pump组(P<0.05)。结论两组患者麻醉效果满意
3、,OPCAB手术对麻醉要求更高。与传统CABG手术相比,OPCAB术后并发症发生率低,恢复更快。14【关键词】体外循环;非体外循环;冠状动脉旁路移植术;麻醉;并发症 ComparisonofAnestheticManagementandEarlyOutcomewithOn-PumpandOff-PumpCoronaryArteryBypassGrafting Abstract:OBJECTIVETocomparetheanestheticmanagementandearlyoutcomeofon-pumpandoff-pumpCABGinaprospectiverandomizedcont
4、rolledtrial.METHODS131consecutiveunselectedpatientsreferredforelectiveprimaryCABGwererandomlyassignedtoaccepteitheron-pump(n=45)oroff-pump(n=86)CABG.Theanestheticmanagementandclinicaloutcomeswerecompared.RESULTSTheoperationtimeinoff-pumpgroupwassignificantlyshorterthanthatinon-pumpgroup[(244±47)minV
5、S.(312±59)min](P<0.05).Thebleedingandfrequencyofneedforbloodorbloodproductstransfusionwashigherinon-pumpgroupcomparedwithoff-pumpgroup(P<0.05).Thenumberofgraftsperformedperpatient[(2.7±0.6)foroff-pumpCABGand(2.9±0.7)foron-pumpCABG]weresimilar.Therewerenohospitaldeathsineithergroup.Theincidence
6、ofperioperativecomplicationsinoff-pumpgroupwassignificantlylesserthanthatinon-pumpgroup(P<0.05).Postoperative14serumCK-MBlevelsincreasedabovenormalvalueinthetwogroups,butitwasmorepronouncedinon-pumpgroup(P<0.05).CONCLUSIONOPCABwithmultiplearterialgraftsisassafeastraditionalCABG.Theincidenceofp
7、erioperativecomplicationsandthepostoperativerecoveryofoff-pumpgroupismoresatisfactorythanthatofon-pumpgroup. Keywords:On-pump;Off-pump;Coronaryarterybypassgrafting;Anesthesia;Complication 传统的冠状动脉旁路移
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