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1、无牙颌对兔颞下颌关节影响的扫描电镜观察?514?现代口腔医学杂志2006年第20卷第5期JModern,~matol,September2006,Vol20,No.5无牙颌对兔颞下颌关节影响的扫描电镜观察龚忠诚林兆全贺多敏马三成【摘要】目的了解牙列缺失后颞下颌关节表面超微结构的变化.方法8只新西兰白兔等量分为四组,一组为对照组,其余三组为实验组,将实验组动物的全口牙拔除,分别于术后1周,16周和26周完整取出双侧颞下颌关节,对其关节盘和髁状突分别用扫描电镜进行观察并与对照组比较.结果牙列缺失后关节盘
2、及髁状突表面均出现明显的退行性改变,其中16周组表现最为突出,主要有凝胶样物质掀起,剥脱,胶原纤维暴露,排列紊乱,关节盘和髁突表面粗糙并出现微小裂孔.26周组关节盘和髁状突表面损伤表现明显减轻.结论牙列缺失可以引起颞下颌关节表面出现退性行改变.【关键词】颞下颌关节无牙颌扫描电镜兔EffectsoftotaledentulousnessolltemporomandibularjointsinrabbiIs:ascanningelectronmicroscopicstudyGONGZhongchengL
3、lNZhaoquan,HEDuomin.ela1.DepartmentofOralandMaxillofacialSurgery.FirstAffiliatedHospital,xinJiangMedicalUniversity,Uru~qi830054【Abstract】ObjectiveToinvestigatetheinfluenceoftotaledentulousnessontemporomandibularjointsinrabbits.MethodsEightNewZealandwhi
4、terabbits(Oryctolaguscuniculus)weredividedintofourgroups,oneofthegroupswasthecontrolandtheotherthreegroupswereservedasexperimentalanimals.Everyexperimentalgroupwassacrificedrespectivelyat1week,16weeksand26weekspostoperativelyandbilateraltemporomandibul
5、arjointswereremovedentirely,thenthediscsandcondylarprocessesofthetemporomandibularjointswereobservedrespectivelyunderascanningelectronmicroscopeResulIsInalltheexperimentalgroups,thesurfaceofthediscsandcondyleswasdegeneratedobviously.Inthe16weekgroup,th
6、echangesoccurredmostapparently.Themainchangesshowedthatthegelatin—likematerialtwistedorevendisappearedonthesurfaceofthediscsandcondyles,thecollagenfiberswereexposedandrankeddisorderedly,somesmallholesandfissurescouldbeseenonthesurfaceofthediscsandcondy
7、leswhichbecametough.However,inthe26weekgroup,thetraumaticchangeswerelessobviousthantheothertwogroupsConclusionTotaledentulousnessmayleadtOtemporomandibularjointdegenerativechanges【Keywords】TemporomandibularjointTotaledentulousnessScanningelectronmicros
8、copeRabbits中图分类号:R7826文献标识码:A颞下颌关节紊乱病(temporomandibularjointdisorders,TMD)是多因素引起的一组疾病.牙齿缺失特别是后牙的缺失以及无牙颌都对TMJ有影响,从而产生一系列TMD临床症状_1J.无牙颌是黯异常的一种特殊表现形式.近年的临床统计资料表明,无牙颌患者有明显的关节疾患【5.6J.在临床实际中,对于无牙颌患者TMJ进行组织学研究相对较为困难.因此,本研究通过对新西兰白兔建立无牙颌模型,在不同时间
