简述特发性全面性癫痫

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1、Descriptionsidiopathicgeneralizedepilepsy（简述特发性全面性癫痫）Idiopathicgeneralizedepilepsyandage-related.SincethecommencementoftheclinicalsymptomsandEEGchangesisbilateralsymmetry,nosignsofnervelocalization,EEGnormalbackgroundactivity.特发性全面性癫痫和年龄有关。临床症状和脑电图变化自开始即为双侧对称，无神经定位体征，脑电图背景活动亦正常。　　(1)benignfamil

2、ialneonatalconvulsionsrare,autosomaldominant,mostborn2to3daysaftertheonsetofclonicepisodes.NospecialEEG.Historyandexaminationnoetiologyfoundthatapproximately14%ofthepatientslaterdevelopedintoatonic-clonicseizures,buttheprognosisisgood.　　(1)良性家族性新生儿惊厥较罕见，为常染色体显性遗传，大多数生后2～3天发病，表现为阵挛或窒息发作。无特殊脑电图表现

3、。病史和检查无病因发现，约14％的患者以后发展为强直--阵挛发作，但预后良好。　　(2)benignneonatalconvulsionsrepeatedclonicortheepisodesmostcommon,andnoknowncauseandmetabolicdisordersappearedaboutfivedaysafterbirth.InterictalEEGoftenvariablesharpwaves,norecurrent.Psychomotordevelopmentalunaffected.　　(2)良性新生儿惊厥以出生后第5天左右出现反复阵挛或窒息发作最为常见

4、，无已知病因和代谢障碍。发作间期脑电图常有可变的尖波，无反复发作。精神运动方面发育不受影响。　　(3)benignmyoclonicepilepsyofinfancybornafter1to2yearsoldtransientgeneralizedmyoclonicseizures,oftenconvulsionsorafamilyhistoryofepilepsy.TheearlysleepEEGrecordsshowbriefuniversalityspine-slowwave,pubertymayoccurtonic-clonicseizures,appropriatetrea

5、tmentiseasytocontrol.Mayhaveacertaindegreeofintelligenceretardationandmildpersonalitydisorder.　　(3)婴儿期良性肌阵挛癫痫出生后1～2岁出现短暂性全身肌阵挛发作，常有惊厥或癫痫家族史。早期睡眠脑电图记录显示短暂普遍性棘—慢波，青春期可能发生强直—阵挛发作，适当治疗易于控制。可有一定程度智能发育迟滞和轻度人格障碍。　　(4)childhoodabsenceepilepsy(frequentabsencepetitmal)isfoundinthe6to7-year-oldschool-agec

6、hildren,morecommoninwomen,significantgeneticpredisposition,autosomaldominantinheritancewithincompletepenetrancecharacterizedbyfrequentabsencessmallattackseveraltimesadaytodozensofadultmaybecured,orcontinuetohaveonlyabsenceseizuresortonic-clonicseizures.EEGshowed3Hzspike-slowwave,normalbackgroun

7、d,caninducehyperventilation.　　(4)儿童期失神癫痫(频发失神小发作)见于6～7岁学龄儿童，女性多见，有明显遗传素质，呈常染色体显性遗传伴不全外显率，特征为频繁失神小发作，每日数次至数十次，成年时可能痊愈，或继续只有失神发作或转化为强直一阵挛发作。脑电图示3Hz棘—慢波，背景正常，过度换气可诱发。　　(5)pubertyabsenceseizuresonthetype,etiologyandgenetic.Factors.Inc