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时间:2020-05-08
《乳腺癌80例疗效分析-论文.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·884·中华实用诊断与治疗杂志2014年9月第28卷第9期JChinPractDiagnTher,September2014,V01.28,No.9·论著·乳腺癌80例疗效分析臧元星(河南省直第一医院外科,郑州45OOO3)摘要:目的探讨不同分期乳腺癌的手术治疗方法及综合治疗效果。方法8O例乳腺癌患者依据其临床分期、肿瘤大小等采用不同手术方式治疗,其中4例I期乳腺癌患者行保乳乳腺癌切除术,2O例Ⅱ~Ⅲ期乳腺癌伴腋窝1、2组淋巴结肿大者行乳腺癌改良根治术,49例伴腋窝1、2、3组淋巴结肿大者行乳腺癌根治术,l例Ⅲe期及6例Ⅳ期患者行姑息性全乳房切除术。术后除I期4例外,均行化、放疗等辅助治疗
2、。随访5a观察存活率。结果4例行保乳乳腺癌切除术者均存活;20例行乳腺癌改良根治术者存活1O例,生存率5O.oO;49例行乳腺癌根治术者存活41例,生存率83.67;7例行姑息性全乳房切除术者存活2例,生存率28.57。6O例肿瘤直径<3cm者术后5a生存率(86.67)高于2O例直径>3cm者(25.00)(P3、,theFirstProvincialHospitalofHenanProvince,Zhengzhou450003,China)Abstract:ObjectiveToexplorethesurgicaltreatmentandresultsofcomprehensivetreatmentofbreastcancerindifferentstages.MethodsEightypatientswithbreastcancerwereperformedoperationsaccordingtoclinicalstagingandtumorsize.In80patientswithbreast4、cancer,4instage1wereperformedsimplemastectomy,20instage1ItoIlIcomplicatedwithgroup1and2axillarylymphadenectasismodifiedradicalmastectomyand49instageⅡtolIcomplicatedwithgroup1,2and3axillarylymphadeneetasiswererespectivelyperformedradicalmastectomy,and1ofstage1ICand6ofstageIVunderwentpalliativetotalm5、astectomy.Seventy—sixpatientsreceivedchemotherapyorradiotherapyafteroperationexcept4patientsinstageI.Allpatientswerefollowedupfor5yearstoobservethesurvivalrate.ResultsFourpatientssurvivedaftersimplemastectomy.In2Opatientsreceivingmodifiedradicalmasteetomy,10survived(50.00).In49patientsreceivingradi6、calmastectomy。41survived(83.67).In7patientsreceivingpalliativebreastcancerresection,2survived(28.57).The5-yearsurvivalratein60patientswithtumordiameter<3cmwas86.67,higherthanthatin20patientswithtumordiameter>3cm(25.00)(P<0.05).ConclusionForpatientswithbreastcancerinstage1andover,radicalmastectomyor7、modifiedradicalmastectomyplusadjuvantradiotherapyorchemotherapycanimprovethe5-yearsurvivalrate.Keywords:Breastcancer;operation;survivalrate乳腺癌为临床常见恶性肿瘤之一,近年发病率有病程8~12(9.6±2.5)a。80例中乳腺浸润性导管癌所增长且呈年轻化趋势Ⅲ。手术是治疗
3、,theFirstProvincialHospitalofHenanProvince,Zhengzhou450003,China)Abstract:ObjectiveToexplorethesurgicaltreatmentandresultsofcomprehensivetreatmentofbreastcancerindifferentstages.MethodsEightypatientswithbreastcancerwereperformedoperationsaccordingtoclinicalstagingandtumorsize.In80patientswithbreast
4、cancer,4instage1wereperformedsimplemastectomy,20instage1ItoIlIcomplicatedwithgroup1and2axillarylymphadenectasismodifiedradicalmastectomyand49instageⅡtolIcomplicatedwithgroup1,2and3axillarylymphadeneetasiswererespectivelyperformedradicalmastectomy,and1ofstage1ICand6ofstageIVunderwentpalliativetotalm
5、astectomy.Seventy—sixpatientsreceivedchemotherapyorradiotherapyafteroperationexcept4patientsinstageI.Allpatientswerefollowedupfor5yearstoobservethesurvivalrate.ResultsFourpatientssurvivedaftersimplemastectomy.In2Opatientsreceivingmodifiedradicalmasteetomy,10survived(50.00).In49patientsreceivingradi
6、calmastectomy。41survived(83.67).In7patientsreceivingpalliativebreastcancerresection,2survived(28.57).The5-yearsurvivalratein60patientswithtumordiameter<3cmwas86.67,higherthanthatin20patientswithtumordiameter>3cm(25.00)(P<0.05).ConclusionForpatientswithbreastcancerinstage1andover,radicalmastectomyor
7、modifiedradicalmastectomyplusadjuvantradiotherapyorchemotherapycanimprovethe5-yearsurvivalrate.Keywords:Breastcancer;operation;survivalrate乳腺癌为临床常见恶性肿瘤之一,近年发病率有病程8~12(9.6±2.5)a。80例中乳腺浸润性导管癌所增长且呈年轻化趋势Ⅲ。手术是治疗
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