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1、无创呼吸机治疗慢性阻塞性肺疾病合并左心衰竭的疗效观察［摘要］目的观察采用无创呼吸机辅助通气治疗AECOPD合并左心衰竭的临床疗效。方法将本院2010年9月〜2012年12月收治的116例AECOPD合并左心衰竭患者随机分为两组，对照组54例给予常规药物治疗,治疗组62例在常规药物治疗基础上采用无创呼吸机辅助通气治疗。观察两组患者治疗后2h、24h、7d的呼吸频率（RR）、心率（HR）、收缩压（SB卩）、指脉氧（SP02）.血气分析、BN卩变化，分析比较两种方法的疗效。结果两组经2h、24h、7d,治疗后，Pa02>pH值较治疗前均有明显升高，PaCO2则较治疗前均降低（P0.05
2、）,但治疗7d后治疗组BNP下降较对照组明显，差异有统计学意义（卩〈0.05）。结论无创呼吸机辅助通气治疗可有效改善AECOPD合并左心衰竭患者的缺氧状态，缓解呼吸机疲劳,提高抢救成功率。［关键词］无创呼吸机；慢性阻塞性肺疾病；左心衰竭［中图分类号］R563［文献标识码］B［文章编号］2095-0616（2013）15-35-03Efficacyobservationofnon-invasiveventilationtreatmentofchronicobstructivepulmonarydiseasecomplicatedbyleftheartfailureZHANGChen
3、DepartmentofInternalMedicine,ZhengzhouTrafficIlospitai,Zhengzhou450001,China[Abstract]ObjectiveToobservetheclinicalefficacyofthenon-invasiveventilationtreatmentoftheacuteexacerbationchronicobstructivepulmonarydisease(AECOPD)complicatedbyleftheartfailure.Methods116patientswithAECOPDcomplicated
4、byleftheartfailurewhoweretreatedinourhospitalfromSeptember2010toDecember2012wererandomlydividedintotwogroups.The54patientsofthecontrolgroupweregivenconventionaldrugtreatmentandthe62patientsofthetreatmentgroupweregivennon-invasiveventilationtreatmentonthebasisoftheconventionaltreatment.Theresp
5、iratoryrate(RR),heartrate(HR),systolicbloodpressure(SBP),saturationpulseoxygen(SPO2),bloodgasanalysisandBNPchanges2hours,24hoursand7daysafterthetreatmentofthetwogroupswereobserved.ResultsAfter2hours,24hoursand7daysoftreatment,thePa02andplIvaluesofbothgroupselevatedsignificantlycomparedtothose
6、beforethetreatment,whilethePaC02valuesofbothgroupsdecreasedcomparedtothosebeforethetreatment(卩0・05)•After2hoursand24hoursoftreatment,thetreatmentgroupandthecontrolgrouphadsimilarBNPimprovementsituation,withnostatisticallysignificantdifference(P>0.05),butafter7daysoftreatment,theBNPofthetreatm
7、entgroupdecreasedsignificantlycomparedtothatofthecontrolgroup,withstatisticallysignificantdifference(P［Keywords］Noninvasiveventilator；Chronicobstructivepulmonarydisease；Leftheartfailure慢性阻塞性肺疾病急性加重期(AEC0PD)是以不完全可逆的气流受限为特征的慢性气道炎症性疾病,呈进行性发展。由于反
