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1、利多卡因表面麻醉与静脉用药预防气管插管反应的临床观察doi：10.3969/j.issn.l007-614x.2014.22.30摘要目的：观察不同方法应用利多卡因预防气管插管反应的有效性实用性。方法：选择ASAI〜II级患者45例，年龄18〜60岁，随机分为3组，A组无表面麻醉、无静脉注射利多卡因，B组2%利多卡因3ml咽喉部气管内表面麻醉，C组2%利多卡因1mg/kg静脉注射。记录麻醉诱导前、气管插管前（即准备行气管插管时）以及气管插管后lmin血压、心率的变化以及呛咳反应的情况。结果：3组患者气管插管前SBP、DBP、HR均明显下降（P0.05）；A组在气管插管后
2、1min较麻醉诱导前及气管插管前SBP、DBP、HR明显增加，差异有统计学意义（P0.05）,气管插管时出现呛咳反应2例。C组患者气管插管反应不大，气管插管后1min较气管插管前SBP、DBP、HR无明显变化，差异无统计学意义（P>0.05）,气管插管时没有出现呛咳反应。结论：利多卡因静脉注射与表面麻醉均能预防气管插管反应，但静脉注射较表面麻醉更能有效预防气管插mi!1!管反应，且给药方便实用性强。关键词利多卡因；静脉注射；表面麻醉；插管反应Clinicalobserva廿onoflidocainesurfaceanesthesiaandintravenousdrugu
3、seinthepreventionofendotrachealintubationresponseChengHui,PengYunxiaDepartmentofAnesthesiology,thePeople'sHospitalofShimianCounty,Ya"anCity,Sichuan625400Abstractobjective：Toobservetheeffectivenessandpracticabilityofdifferentmethodsofapplicationoflidocaineinthepreventionofendotrachealintu
4、bationresponse.Methods：45casesofASAI〜IIwereselected.Theagewas18〜60yearsold.Theywererandomlydividedinto3groups.Agroupwasnosurfaceanesthesia,nointravenouslidocaine.Bgroupweregiven2%lidocaine3mlthroattrachealsurfaceanesthesia.Cgroupweregiven2%lidocainelmg/kgintravenousinjection.Beforeanesth
5、esiainduction,beforeendotrachealintubation(preparelineendotrachealintubation)and1minuteafterendotrachealintubatiorbthechangeofbloodpressure,heartrateandchokingcoughresponsewererecorded.Results：Beforeendotrachealintubation,SBP,DBP,HRof3groupswereallsign讦icantlydecreased(P0.05)minuteaftere
6、ndotrachealintubation,SBP,DBP,HRofAgroupwereobviouslyincreasedthanthosebeforeanesthesiainductionandbeforeendotrachealintubation；therewassignificantdifferenee(P0.05)・2casesappearedchokingcoughresponsewhentrachealintubation.TheendotrachealintubationreactionsofpatientsinCgroupwerelittle.1mi
7、nuteafterendotrachealintubation,SBP,DBP,HRwerenoobviouschangecomparedwithbeforeendotrachealintubation,andtherewasnosignificantdifferenee(P>0.05)・No1caseappearedchokingcoughresponsewhentrachealintubation.Conclusion：Lidocaineintravenousinjectionandsurfaceanesthesiacanpreven
