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ID:36533556
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页数:8页
时间:2019-05-11
《钬激光下肢静脉曲张腔内治疗临床研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、钬激光下肢静脉曲张腔内治疗临床研究作者:褚雪峰,缪秀华,圣小平,张松贵,许晓萍,陈正言【摘要】目的:探讨钬激光治疗下肢静脉曲张的机理。方法:(1)对经钬激光治疗术后的下肢静脉曲张患者进行彩色多谱勒超声监测;(2)对离体大隐静脉进行实验,比较大隐静脉内不同介质在钬激光作用于血管壁过程中的影响;(3)活体治疗后的大隐静脉段病理检查;(4)术前术后血D-二聚体、纤维蛋白原值比较分析。结果:(1)治疗后大隐静脉腔内即见实性回声,随诊发现回声逐渐增强,大隐静脉内径均比术前有不同程度缩小,腔内无血流信号;(2)、病理显示,钬
2、激光治疗后大隐静脉内皮消失,内、中、外膜均不同程度的变性、坏死;(3)血管内不同介质直接影响钬激光对血管壁的作用结果;(4)手术前、后血D-二聚体值比较差异有统计学意义(P﹤0.01),纤维蛋白原值比较差异有统计学意义(P﹤0.05)。结论:钬激光可诱导静脉壁增厚、挛缩、内径缩小,最终静脉闭锁。血液是钬激光作用于血管壁过程中的必需介质,术后存在有高凝状态。【关键词】下肢静脉曲张;钬激光;彩色多普勒超声检查;酶联免疫吸附试验[Abstract]Objective:Toresearchthemechanismof8t
3、reatmentforthephlebeurysmalowerlimbswithholmiumlaser.Methods:(1)ColourDopplersupersonicmonitoringwascarriedoutonthepatientstreatedforphlebeurysmalowerlimbswithholmiumlaser.(2)Experimentswereconductedongreatersaphenousveininvitro;Theeffectsofdifferentmediaingr
4、eatersaphenousveinwerecomparedwhenholmiumlaserwasaffectingthebloodvesselwall.(3)Pathologicalexaminationswereconductedonthegreatersaphenousveinsectionaftertreatingthelivingbody.(4)ContrastandanalysisofD-dimerandhemaleucinoriginalvalueinbloodweremadebeforeandaf
5、teroperation.Results:(1)Therewassubstantiveechoingreatersaphenousveinsoonafterthetreatment.Thesubstantiveechobecamestrongwhenreexamined.Theboresizebecamesmallerinsomeways.Andtherewasnosignofbloodflowinthecavity.(2)Pathologicalmechanismshowedthatthebastingreat
6、ersaphenousveindisappearedafterbeingtreatedbyholmiumlaser.Theinner,middleandoutermembranesalldenaturatedornecrosedinsomeways.(3)Differentmediainbloodvesselaffectedtheeffectofholmiumlaseronbloodvesselwalldirectly.(4)TherewasaremarkabledifferenceinD-dimer(P<
7、0.01)andhemaleucinoriginalvalue(P<0.05)inbloodbeforeandaftertheoperation.Conclusion:Holmiumlasercan8leadtothrombosisingreatersaphenousvein.Withdestroyingthenormalstructureofbloodvesselwall,itcausesthedamagedveinwalltobecomethickerandcontract.Thustheboresiz
8、ebecomesnarrower.Atlasttheveinisshutting.Bloodisthenecessarymediumwhenholmiumlaserisaffectingthebloodvesselwall.Bloodcongealsquickerafteroperation.[Keywords]Phlebeurysmalowerlimbs;Holmium
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